Tekmira Pharmaceuticals Company Profile

22:32 EDT 21st March 2018 | BioPortfolio

Tekmira Pharmaceuticals Corporation is a publicly-traded (NASDAQ:TKMR, TSX:TKM) biopharmaceutical company located in Vancouver, Canada. Recognized as a world leader in RNA interference (RNAi) delivery technology, we are focused on advancing novel RNAi-based product candidates. RNA interference, or RNAi, is considered one of the most important discoveries in the field of biomedical science in the last decade. RNAi has the potential to generate a new class of therapies to take advantage of the body’s own natural processes to silence genes and, by extension, treat serious human diseases that often rely on the production of certain proteins at the genetic level. This method of treatment is not currently available with conventional drugs. Tekmira’s proprietary LNP Delivery Platform makes possible the successful delivery and enablement of RNAi drugs. Leadership in the area of delivery has enabled us to establish long-term, revenue generating partnerships with global leaders in the field. In addition to advancing our own drug pipeline, we support our partners as they develop this new class of drugs using our leading delivery technology.

Tekmira’s Lipid Nanoparticle (LNP) technology represents the most widely adopted RNAi delivery technology to date. Administered intravenously, our LNP delivery technology allows RNAi drugs to be encapsulated in tiny particles made of lipids (fats or oils). These tiny particles – LNP – travel through the bloodstream to target tissues. LNPs are designed to stay in the circulation long enough to accumulate at disease sites, such as the liver or cancerous tumors. Through a process called endocytosis, cells take up the LNPs which allows them to migrate into the cell. The LNPs then undergo an interaction within the cell and the siRNA drug is released, mediating RNAi.


Pipeline Products


100 - 8900 Glenlyon Parkway
British Columbia
V5J 5J8


Phone: 604.419.3200
Fax: 604.419.3201

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