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Cell Signaling Technologies Company Profile

15:41 EDT 23rd September 2018 | BioPortfolio

Founded by research scientists in 1999, CST is a private, family-owned company with over 400 employees worldwide. Active in the field of applied systems biology research, particularly as it relates to cancer, CST understands the importance of using antibodies with high levels of specificity and lot-to-lot consistency. We produce all of our antibodies in house, and perform painstaking validations for multiple applications. Technical support is provided by the same CST scientists who produce our antibodies, helping customers design experiments, troubleshoot, and achieve reliable results. CST is certified by BSI to be compliant with ISO 9001:2008 for the design, development, and production of monoclonal antibodies. Information about CST is available at www.cellsignal.com.


News Articles [1891 Associated News Articles listed on BioPortfolio]

Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells

Expression of the B-cell antigen receptor (BCR) is essential not only for the development but also for the maintenance of mature B cells. Similarly, many B-cell lymphomas, including Burkitt lymphoma (...

New chemo-optogenetic method enables multi-directional activity control of cellular processes

Cells need for reactions on environmental changes and a balanced system of signaling cascades within the cell. Proteins outside of the cell, on the cellular surface, inside the cellular membrane, and ...

Human Cell Line for Studies on Signaling and Endocrine Cancer

The first known immortalized cell line with a naturally-occurring inactivating mutation in PRKAR1A, the regulatory subunit type 1A (R1alpha) of protein kinase A (PKA), which is associated with tumor f...

YAP-TEAD signaling promotes basal cell carcinoma development via a c-JUN/AP1 axis

The mammalian Hippo signaling pathway, through its effectors YAP and TAZ, coerces epithelial progenitor cell expansion for appropriate tissue development or regeneration upon damage. Its ability to dr...

Muddied by Mutations, or Drugs, Cell Signaling Can Herald Cancer

The quality of a cell signal, not just its strength, can determine whether a cell will follow a path toward cancer. This finding, which emerged from optogenetic interrogations of both healthy cells an...

Uncovering a hidden protein 'tail' that puts the brakes on cell signaling

(Georgia Institute of Technology) Using an informatics tool that identifies "hotspots" of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechan...

Cells Communicate with Each Other to Stop Cancer

NewsResearch into cell-to-cell signaling mechanism may lead to new cancer treatments.

Stem Cell Sciences: Stem Cell Technologies: The End of the Beginning

In this exclusive interview, Fintan Walton talks to Peter Mountford, formerly CEO of Stem Cell Sciences, about the current state of stem cell technologies and their potential healthcare and research a...

PubMed Articles [6017 Associated PubMed Articles listed on BioPortfolio]

B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells.

Type 1 interferon (T1IFN) signaling promotes inflammation and lupus pathology, but its role in autoreactive B cell development in the antibody-forming cell (AFC) and germinal center (GC) pathways is u...

The Domino Effect in EGFR-ERK Signaling.

A gradient of EGFR-ERK signaling has been classically implicated in various developmental processes. In this issue of Developmental Cell, Ogura et al. (2018) show that in the Drosophila tracheal plac...

The impact of single-cell RNA sequencing on understanding the functional organization of the immune system.

Application of single-cell genomics technologies has revolutionized our approach to study the immune system. Unravelling the functional diversity of immune cells and their coordinated response is key ...

Wnt signaling in development and tissue homeostasis.

The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication system that is important for stem cell renewal, cell proliferation and cell differentiation both during embr...

Comparative Analysis of Regulatory Role of Notch Signaling Pathway in 8 Types Liver Cell During Liver Regeneration.

Notch signaling is closely related to cell proliferation, cell apoptosis, cell fate decisions, DNA damage repair, and so on. However, the exactly regulatory mechanism of Notch signaling pathway in liv...

Clinical Trials [6931 Associated Clinical Trials listed on BioPortfolio]

Occupational Exposure to Pesticides in the Prognosis of Lymphomas

The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor ...

Osteoclast Inhibition and Bone Formation

This protocol addresses: 1) How gene expression changes in bone cells are affected by aging? 2) Is aging associated with decreased signaling between bone cells? 3) How does treatment with ...

Establishment of Comprehensive Genetic Analysis From a Single Cell

Preimplantation genetic diagnosis (PGD) is the integration of both assisted reproductive technologies and molecular genetic technologies and was shown to improve implantation rate and redu...

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

The investigators are examining the activation of insulin signaling factors in skeletal muscles of human diabetics. The investigators are characterizing the defects in signaling, and are e...

Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients

The purpose of this study is to demonstrate that orally administered itraconazole, a commonly used antifungal medication, can inhibit Hedgehog pathway signaling in patients with esophageal...

Companies [2305 Associated Companies listed on BioPortfolio]

Complexa, Inc.

Complexa, Inc. is a platform biopharmaceutical company researching and developing endogenous human cell signaling technologies targeting an array of prevalent inflammatory and met...

BioImage A/S

BioImage A/S uses its expertise in redistributionâ„¢ technologies to discover drug candidates that change the activity of specific signaling pathways without inhibiting the catalytic activity of s...

Cell Signaling Technology, Inc.

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned f...

Echelon Biosciences Incorporated

Echelon Biosciences was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, and was incorporated under the laws of the state of Utah as Echelon Research La...

Arbor Vita Corporation.

Arbor Vita is a biopharmaceutical company focused on the discovery, development and commercialization of novel drugs and diagnostics addressing disease through a new family of targets, PDZ proteins. P...

More Information about "Cell Signaling Technologies" on BioPortfolio

We have published hundreds of Cell Signaling Technologies news stories on BioPortfolio along with dozens of Cell Signaling Technologies Clinical Trials and PubMed Articles about Cell Signaling Technologies for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Cell Signaling Technologies Companies in our database. You can also find out about relevant Cell Signaling Technologies Drugs and Medications on this site too.

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