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Aegerion Pharmaceuticals, Inc. Company Profile

21:49 EDT 19th June 2018 | BioPortfolio

Aegerion Pharmaceuticals is a biopharmaceutical company dedicated to the development and commercialization of innovative, life-altering therapies for patients with debilitating often fatal, rare diseases.

Therapeutic focus

Homozygous familial hypercholesterolemia (HoFH) is the most severe form of familial hypercholesterolemia. HoFH is caused by genetic defects inherited from both parents that affect the function of the low-density lipoprotein (LDL) receptor, the receptor responsible for removing LDL-C cholesterol (bad cholesterol) from the body. HoFH is characterized by extremely high levels of LDL cholesterol (LDL-C). HoFH is typically diagnosed by LDL-C levels, physical exam and family history.

National guidelines recommend LDL-C goals of less than 100 mg/dL (2.6 mmol/L) for patients at high risk for CVD and less than 70 mg/dL (1.8 mmol/L) for patients at very high risk.

Location

101 Main Street
Suite 1850
Cambridge
MA
MA 02142
USA

Contact

Phone: 1-855-305-2347
Fax: 1-617-945-7968
Email: infogroup@aegerion.com


News Articles [498 Associated News Articles listed on BioPortfolio]

Doctor admits disclosing patient info to drugmaker Aegerion

BOSTON (Reuters) - A Georgia pediatric cardiologist pleaded guilty on Wednesday to wrongfully disclosing information about his young patients to an Aegerion Pharmaceuticals Inc sales representative se...

U.S. judge sentences Novelion's Aegerion in drug marketing case

BOSTON (Reuters) - A federal judge on Tuesday sentenced Aegerion Pharmaceuticals Inc for improperly marketing a cholesterol drug and ordered that some of the $40.1 million it agreed to pay to resolve ...

Amryt, Aegerion sign expanded deal for Lojuxta capsules

Amryt has signed an agreement with Aegerion Pharmaceuticals to expand its exclusive licence agreement for Lojuxta (lomitapide) into Russia and the Commonwealth of Independent States (CIS), as well as ...

Orphan drug specialist Amryt Pharmaceuticals appoints chief commercial officer

David Allmond has been brought in from Aegerion Pharmaceuticals, where he worked with the recently in-licensed Lojuxta

Aegerion enters into $20mm term loan agreement

Novelion Therapeutics Inc.'s Aegerion Pharmaceuticals Inc. subsidiary entered into a $20mm term loan agreement with Sarissa Capital Management and Broadfin Capital. The loan accrues interest at 9% per...

Aegerion sentenced for mismarketing of cholesterol drug

A federal judge, who had rejected the initial plea deal in November, ordered $7 million of the $40 million penalty be paid to Aegerion's victims.

Novelion Therapeutics Announces Sentencing of Subsidiary Aegerion Pharmaceuticals

VANCOUVER, British Columbia, Jan. 30, 2018 (GLOBE NEWSWIRE) -- Novelion Therapeutics Inc. (NASDAQ:NVLN), a biopharmaceutical company dedicated to developing new standards of care for individual...

Amryt Pharma appoints Jordi Casals as head of Europe

He joins the company from Aegerion Pharmaceuticals

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PubMed Articles [133 Associated PubMed Articles listed on BioPortfolio]

Letter--Incorporating Real-World Evidence and Patient Value Criteria into Value-Based Frameworks for Relapsed/Refractory Multiple Myeloma.

Orlowski has received research funding from Amgen, BioTheryX, Bristol-Myers Squibb, Celgene Corporation, and Takeda Pharmaceuticals; honoraria from Amgen, Bristol-Myers Squibb, Celgene Corporation, Ja...

Genetics of familial hypercholesterolemia: a tool for development of novel lipid lowering pharmaceuticals?

Familial hypercholesterolemia is characterized by high LDL cholesterol and an elevated risk to develop coronary heart disease. Mutations in LDL receptor-mediated cholesterol uptake are the main cause ...

Post-production handling and administration of protein pharmaceuticals and potential instability issues.

The safety and efficacy of protein pharmaceuticals depend not only on biological activity, but also on purity levels. Impurities may be process related due to limitations in manufacturing, or product ...

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines and Pharmaceuticals.

Methods to incorporate deuterium and tritium atoms into organic molecules are valuable for medicinal chemistry. The prevalence of pyridines and diazines in pharmaceuticals means that new ways to label...

Environmental concentrations of pharmaceuticals directly affect phytoplankton and effects propagate through trophic interactions.

Pharmaceuticals are found in freshwater ecosystems where even low concentrations in the range of ng Lmay affect aquatic organisms. In the current study, we investigated the effects of chronic exposure...

Clinical Trials [215 Associated Clinical Trials listed on BioPortfolio]

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic®20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sep...

Bioequivalence Study of Torrent Pharmaceuticals's Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic 20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sepa...

Study Comparing Citalopram Hydrobromide Tablets 40 mg (Torrent Pharmaceuticals Ltd) and RLD Tablets 40 mg (Manufactured By Forest Pharmaceuticals Inc, Missouri) in 24+2 Normal Healthy Male Subjects in Fed Condition

- Objective: - The objective of this study is to compare the rate and extent of absorption of the Test Product, Citalopram Hydrobromide 40 mg (Torrent Pharmaceutical Li...

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Rosuvastatin Calcium Tablets Under Fed Conditions

Subjects to compare the single dose bioavailability of Torrent's Rosuvastatin Calcium Tablets 40 mg and Crestor® 40 mg Tablets of AstraZeneca Pharmaceuticals LP, USA. Dosing periods of st...

Cilostazol 50 mg Tablets Under Fasting Conditions

This study will compare the relative bioavailability (rate and extent of absorption) of 50 mg Cilostazol Tablets manufactured by TEVA Pharmaceuticals Industries Ltd. and distributed by TEV...

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More Information about "Aegerion Pharmaceuticals, Inc." on BioPortfolio

We have published hundreds of Aegerion Pharmaceuticals, Inc. news stories on BioPortfolio along with dozens of Aegerion Pharmaceuticals, Inc. Clinical Trials and PubMed Articles about Aegerion Pharmaceuticals, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Aegerion Pharmaceuticals, Inc. Companies in our database. You can also find out about relevant Aegerion Pharmaceuticals, Inc. Drugs and Medications on this site too.

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Biopharmaceuticals
Biopharmaceuticals are medical drugs produced using biotechnology. They include proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) and living microorganisms like virus and bacteria where the virulance of viruses and b...


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