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4D Molecular Therapeutics Company Profile

12:59 EDT 20th September 2018 | BioPortfolio

4DMT is a global leader in gene therapy product research & development. 4DMT and our partners are using scientific innovation to unlock the full potential of gene therapy for patients with genetic diseases. Our robust discovery platform, termed Directed Vector Evolution, empowers us to create customized gene delivery vehicles (novel AAV vectors) to deliver genes to any tissue or organ in the body. These customized products allow us to deliver normal genes to tissues with defective genes (as occurs in genetic diseases). This 4DMT discovery technology was originally developed over 15 years by our co-Founder David Schaffer at the University of California, Berkeley. In contrast to first-generation vectors, our customized 4D vectors target specific patient tissues in a highly efficient and targeted fashion, while avoiding other tissues and resisting immune clearance (by pre-existing antibodies). 4D has a robust and growing product pipeline, including partnered programs with our collaborators at Roche and uniQure. Our management team, led by co-Founder & CEO Dr. David Kirn, has the most experience in the industry in viral vector gene therapy R&D, clinical development, entrepreneurship and business development. 4D Molecular Therapeutics is based in the QB3@953 and JLABS laboratories in the Mission Bay area of San Francisco, a world-class hub for biomedical innovation.


News Articles [1223 Associated News Articles listed on BioPortfolio]

4D Molecular Therapeutics Scores $90 Million in Series B Funding

4D Molecular Therapeutics snagged $90 million in a Series B financing round. The company intends to use the funds to advance its Therapeutic Vector Evolution platform and pipeline of next-generation A...

4D Molecular Therapeutics And MedImmune Collaborate To Design, Develop, And Commercialize AAV Gene Therapy

NewsMedImmune, the global biologics research and development arm of AstraZeneca, and 4D Molecular Therapeutics announced a collaboration to develop and commercialize a gene therapeutic for patients wi...

MedImmune and 4D Molecular Therapeutics Collaborate on AAV Gene Therapy for Lung Disease

AstraZeneca’s MedImmune and 4D Molecular Therapeutics forged a collaboration to develop a gene therapy for chronic lung disease.

AstraZeneca and 4D Molecular Therapeutics explore gene therapy for lung disease

AstraZeneca and 4D Molecular Therapeutics have formed a collaboration to develop a gene therapy for patients with chronic lung disease.

On Cusp of Gene Therapy Clinical Trial, 4D Molecular Reels In $90M

4D Molecular Therapeutics is already working with several large pharmaceutical companies to help them develop new gene therapies. Now, as its own gene therapy candidate approaches clinical trials, the...

4D Molecular raises $90mm in Series B round

4D Molecular Therapeutics (adeno-associated virus (AAV) gene therapy) raised $90mm in its Series B financing round.

Molecular Templates Reports First Quarter 2018 Financial Results

Molecular Templates (Nasdaq:MTEM) a clinical-stage oncology company focused on the discovery and development of the company’s proprietary engineered toxin bodies (ETBs), which are differentiated, ta...

The Molecular Autopsy: Not Ready Yet for Prime Time

Although I have always been a strong advocate for sophisticated molecular and genomic testing, I tend to get a severe case of indigestion when I see references to the molecular autopsy (see: Can Inter...

PubMed Articles [1206 Associated PubMed Articles listed on BioPortfolio]

Intrinsically Disordered Proteins: Structure, Function and Therapeutics.

Molecular targeted therapy: treating cancer with specificity.

Molecular targeted therapies are revolutionized therapeutics which interfere with specific molecules to block cancer growth, progression and metastasis. Many molecular targeted therapies approved by t...

RNA Therapeutics (Almost) Comes of Age: Targeting, Delivery and Endosomal Escape.

Significance of Pharmacogenomics in Precision Medicine.

Precision medicine-a term widely used in modern medicine-emphasizes the goal to overcome still existing limitations of therapeutic interventions by tailoring medical treatments to individual patient c...

Recent developments in intracellular protein delivery.

Protein therapeutics based on transcription factors, gene editing enzymes, signaling proteins and protein antigens, have the potential to provide cures for a wide number of untreatable diseases, but c...

Clinical Trials [1459 Associated Clinical Trials listed on BioPortfolio]

Multi-Drug Resistant Organism Network

This study is specifically designed to provide observational data which can be used to help in the design of future randomized clinical trials on both therapeutics and diagnostics for MDRO...

Initiative for Molecular Profiling in Advanced Cancer Therapy (IMPACT) Trial, An Umbrella Protocol

Primary Objective The primary objective of this study is to establish a program for the molecular profiling of patients with advanced cancer, with the goals of (1) providing a comprehensiv...

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Cognitive Dysfunction in MS: Using Altered Brain Oscillation to Link Molecular Mechanisms With Clinical Outcomes

Up to 65% of patients with multiple sclerosis (MS) experience cognitive dysfunction. Diminution of mental capacity has a pervasive and profound impact on their quality of life. Subtle chan...

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More Information about "4D Molecular Therapeutics" on BioPortfolio

We have published hundreds of 4D Molecular Therapeutics news stories on BioPortfolio along with dozens of 4D Molecular Therapeutics Clinical Trials and PubMed Articles about 4D Molecular Therapeutics for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of 4D Molecular Therapeutics Companies in our database. You can also find out about relevant 4D Molecular Therapeutics Drugs and Medications on this site too.

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