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Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc. Company Profile

03:18 EDT 18th June 2019 | BioPortfolio

Nivalis Therapeutics, Inc. (http://www.nivalis.com) is a pharmaceutical company that has historically been focused on the discovery and development of product candidates for patients with cystic fibrosis, or CF. The Company’s development candidates selectively target an enzyme known as S-nitrosoglutathione reductase (GSNOR). GSNOR regulates levels of an endogenous protein known as S-nitrosoglutathione (GSNO). Depleted levels of GSNO have been associated with CF, asthma, inflammatory bowel diseases and certain cardiovascular diseases. Following recent disappointing results of a Phase 2 clinical trial of its lead product candidate, cavosonstat, in CF, Nivalis determined to not pursue the development of this compound in CF and to wind down its research and development activities while devoting its efforts to investigating and evaluating strategic alternatives.


News Articles [2709 Associated News Articles listed on BioPortfolio]

Adaptimmune and Alpine Immune Sciences enter cell therapy deal

Adaptimmune Therapeutics PLC and Alpine Immune Sciences Inc. will work together to discover and develop next-generation T-cell therapies for cancer based on Adaptimmune’s secreted and transmembrane ...

Adaptimmune and Alpine Immune Sciences Partner for Development of Next-Generation SPEAR T-Cell Products Using Alpine’s SIP and TIP Technology

PHILADELPHIA and OXFORDSHIRE, United Kingdom, May 15, 2019 (GLOBE NEWSWIRE) — Adaptimmune Therapeutics plc (Nasdaq:ADAP), a leader in T-cell therapy to treat cancer, and Alpine Immune Sciences, ...

Alpine Immune treats first patient in Phase I trial of ALPN-101

Alpine Immune Sciences has commenced dosing of patients in a Phase I clinical trial of its investigational product ALPN-101 intended...Read More... The post Alpine Immune treats first patient in Phase...

Alpine Immune Sciences to Present at Upcoming Investor Conferences

Alpine Immune Sciences, Inc. (NASDAQ: ALPN), a leading clinical-stage immunotherapy company focused on developing innovative treatments for cancer, autoimmune/inflammatory, and ot...

Adaptimmune, Alpine Immune Sciences Enter Next-Gen SPEAR T-Cell Pact

Adaptimmune to license Alpine’s Immunomodulatory Protein technology for use with SPEAR T-cells to enhance anti-tumor responses

Alpine Immune Sciences: A New Name On The Radar

Private placement brings in $25mm for Alpine Immune

Alpine Immune Sciences Inc. (multifunctional immunotherapies for cancer and autoimmune/inflammatory diseases) grossed $25mm through the private placement of 4.7mm common shares at $5.37 (an 8% premium...

Alpine Immune Sciences Appoints Biopharma Veteran Wayne Gombotz as Chief Technology Officer

Alpine Immune Sciences, Inc. (NASDAQ:ALPN), a leading clinical-stage immunotherapy company focused on developing innovative treatments for cancer, autoimmune/inflammatory, and oth...

PubMed Articles [3028 Associated PubMed Articles listed on BioPortfolio]

Taxonomic re-examination of "Chloromonas nivalis (Volvocales, Chlorophyceae) zygotes" from Japan and description of C. muramotoi sp. nov.

Recent molecular data has strongly suggested that field-collected cysts of snow algae that are morphologically identifiable as the zygotes of Chloromonas nivalis are composed of multiple species. Moti...

Cardiovascular effects and risks of recreational alpine skiing in the elderly.

Alpine skiing is one of the most popular recreational winter sports and attracts millions of tourists every year alone in the Alpine region. Several studies highlight the positive effects of alpine sk...

Analyzing the causes of alpine meadow degradation and the efficiency of restoration strategies through a mathematical modelling exercise.

As an important ecosystem, alpine meadow in China has been degraded severely over the past few decades. In order to restore degraded alpine meadows efficiently, the underlying causes of alpine meadow ...

Soil organic carbon and total nitrogen stocks in alpine ecosystems of Altun Mountain National Nature Reserve in dry China.

The Altun Mountain National Nature Reserve (AMNNR), characterized by complex topography, is located on the northern edge of the Qinghai-Tibetan Plateau. The stocks of soil organic carbon (SOC) and tot...

Immunogenicity of Protein Pharmaceuticals.

Protein therapeutics have drastically changed the landscape of treatment for many diseases by providing a regimen that is highly specific and lacks many off target toxicities. The clinical utility of ...

Clinical Trials [3726 Associated Clinical Trials listed on BioPortfolio]

Effect and Efficacy of Xpedition™/Alpine™, Everolimus-eluting Stent for Coronary Atherosclerosis

The objectives of this study are 1. To establish a prospective registry of the whole patients who received percutaneous coronary intervention with Xience Xpedition™/Alpine™ ste...

10-years Nationwide Alpine Accidents in Austria

This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions. The mechanisms of accidents which are evaluated are lightni...

A 13-years Nationwide Study of Alpine Accidents in Austria

Brief Summary: This observational study intends to analyze the characteristic of specific accidents happened in Austrian's mountainous regions. The mechanisms of accidents which are evalu...

Alpine vs. Xpedition: Evaluation of Stent Delivery System

To evaluate and compare the performance of two stent delivery systems for percutaneous coronary intervention with everolimus-eluting stent.

Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-VII: Sirolimus-eluting (Ultimaster) vs. Everolimus-Eluting Stents (Xience)

This study compares angiographic and clinical outcomes in patients with long coronary lesions treated with sirolimus-eluting stent (Ultimaster stent) or everolimus-eluting stent (Xience Al...

Companies [2848 Associated Companies listed on BioPortfolio]

Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc.

Nivalis Therapeutics, Inc. (http://www.nivalis.com) is a pharmaceutical company that has historically been focused on the discovery and development of product candidates for patie...

Alpine Immune Sciences, Inc.

Alpine Immune Sciences, Inc. was founded in 2015 and is focused on developing novel protein‐based immunotherapies using its proprietary variant immunoglobulin domain (vIgD) p...

Nivalis Therapeutics, Inc.

Nivalis Therapeutics, Inc. (http://www.nivalis.com) is a pharmaceutical company that has historically been focused on the discovery and development of product candidates for patie...

Alpine BioVentures

Alpine BioVentures is a venture capital firm committed to investing in and building revolutionary healthcare companies. It brings a unique perspective to identify game-changing sc...

Alpine Investors

Alpine Investors is a values-driven private equity firm committed to building enduring, purpose-driven companies through its unique PeopleFirst model. Leading with a focus on peop...

More Information about "Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc." on BioPortfolio

We have published hundreds of Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc. news stories on BioPortfolio along with dozens of Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc. Clinical Trials and PubMed Articles about Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc. Companies in our database. You can also find out about relevant Nivalis Therapeutics, Inc. and Alpine Immune Sciences, Inc. Drugs and Medications on this site too.

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