Lodo Therapeutics Corporation Company Profile

02:17 EST 13th November 2018 | BioPortfolio

Lodo Therapeutics Corporation is a drug discovery and development company focused on the creation of novel therapeutics derived from nature that will impact patients around the world. The company was established to pursue the scientific vision of Dr. Sean Brady, head of The Rockefeller University's Laboratory of Genetically Encoded Small Molecules. Lodo Therapeutics identifies and produces bioactive natural products directly from the microbial DNA sequence information contained in soil. Information encoded in bacterial genomes, not experimental serendipity, drives the company’s discovery of new medicines. Not constrained by traditional culture-based approaches to natural products drug discovery, Lodo Therapeutics has unlocked a vast trove of overlooked compounds evolutionarily selected for processes essential for life and with significant potential in the treatment of drug-resistant microbial infections and cancers

News Articles [844 Associated News Articles listed on BioPortfolio]

Roche To Use Lodo Therapeutics' Drug Discovery Platform

NewsUnder the terms of the agreement, Genentech will utilize Lodo Therapeutics’ proprietary genome mining and biosynthetic cluster assembly platform to identify novel molecules with therapeutic pote...

Deal Watch: Genentech Gets Down In The Dirt With Lodo Therapeutics

Genentech and Lodo will mine the soil microbiome to discover novel therapeutics. China’s Luye licenses commercial rights to AstraZeneca’s Seroquel...   

Genentech, Lodo Therapeutics Ink Up-to-$969M Metagenomics Drug Discovery Partnership

Genentech, a member of the Roche Group, will partner with Lodo Therapeutics to develop new drugs based on Lodo’s metagenomics-based natural products drug discovery platform, through a collaboration ...

Genentech, Lodo Therapeutics form $969m drug discovery collaboration

Roche’s subsidiary Genentech has entered into a strategic drug discovery collaboration with Lodo Therapeutics, which is focused on the creation of therapeutics derived from nature that will impact p...

Lodo Therapeutics and Genentech sign multi-target agreement

A multi-target strategic collaboration has been formed between drug discovery and development company, Lodo Therapeutics, and Genentech — a member of the Roche Group.

Lodo partners with Genetech on metagenomics drug R&D

Roche Holding member Genentech and Lodo Therapeutics signed a strategic drug-discovery agreement that aims to develop new dru -More- 

Digging up the dirt: Roche and Lodo ink soil-based discovery deal

If all milestones are hit, the heavily back-ended deal could eventually be worth almost $1 billion for startup Lodo Therapeutics.

Lodo and Roche go digging for drug candidates, after $1bn deal

Discovering potential therapeutics from natural sources has been a constant throughout the evolution of medicine, Lodo Therapeutics, however, has taken it one step further via its soil-sequencing appr...

PubMed Articles [471 Associated PubMed Articles listed on BioPortfolio]

RNA Therapeutics (Almost) Comes of Age: Targeting, Delivery and Endosomal Escape.

RNA-targeted therapeutics for lipid disorders.

To summarize recent developments in the field of RNA-directed therapeutics targeting lipid disorders that are not effectively managed.

A Review of Therapeutics in Clinical Development for Respiratory Syncytial Virus and Influenza in Children.

Respiratory syncytial virus (RSV) and influenza are important viral pathogens worldwide. Children, in particular, bear considerable burdens of morbidity and mortality associated with these viruses. Th...

Pharmacokinetic Analysis of Intraocular Penetration of Latanoprost Solutions with Different Preservatives in Human Eyes.

Eyes on New Product Development.

Clinical Trials [162 Associated Clinical Trials listed on BioPortfolio]

Leukotriene Polymorphisms and Montelukast Response - Ancillary to LoDo Trial

To elucidate the mechanisms underlying inter-patient variation in response to montelukast, a drug for asthma.

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act...

Dobutamine Stress Echocardiography in Cardiac Resynchronization Therapy (CRT) Patients Selection

While cardiac resynchronization therapy (CRT) has a well demonstrated therapeutic effect in selected patients with advanced heart failure (HF) on optimized drug therapy, non-responder rate...

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Drug Discovery
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...

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Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...

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