Zafgen, Inc. Company Profile

22:00 EST 13th December 2018 | BioPortfolio

Zafgen is pioneering novel obesity therapeutics that directly target fat metabolism to help the body regain and sustain a lean, healthy state. The company’s approach focuses on restoring control of key metabolic processes, releasing stored fat which then is used by the body as fuel. Zafgen’s first generation product, named ZGN-433, is being studied in a Phase 1b clinical trial for its use as a pharmacological alternative to bariatric surgery in the treatment of severe obesity. Zafgen's leadership and scientific advisors include leading experts in obesity, metabolic disorders and medicinal chemistry. Founded in 2005, the company is located in Cambridge, Mass. For more information, visit

News Articles [53 Associated News Articles listed on BioPortfolio]

Zafgen Exec Thomas Hughes Resigns to Take CEO Job at Navitor

Thomas Hughes is leaving Zafgen, which he led for nine years, in order to take the top job at another biotech company. The job change comes 10 months after Hughes resigned as CEO of Zafgen (NASDAQ: ZF...

In The Spotlight: Zafgen

Shares of Zafgen Inc. (ZFGN) are up an impressive 129% year-to-date compared to the 4% gain of the iShares Nasdaq Biotechnology ETF (IBB) index during the same period.

FDA Places Clinical Hold on Experimental Diabetes Drug

NewsThe FDA cited the possibility of cardiovascular safety risk with Zafgen, Inc.'s ZGN-1061 and outlined multiple potential paths for moving forward.

Zafgen’s ZGN-1061 for T2D and obesity leaves experts uncertain

Zafgen’s ZGN-1061 leaves experts uncertain about ultimate Phase II trial outcomes in patients with type 2 diabetes (T2D) and obesity considering...Read More... The post Zafgen’s ZGN-1061 for T2D ...

FDA Slaps Clinical Hold on Zafgen’s Lead Product Over Safety Concerns

Shares of Boston-based Zafgen, Inc. plunged more than 32 percent in pre-market trading after the company announced the U.S. Food and Drug Administration has slapped a clinical hold on its plans to lau...

FDA puts Zafgen's diabetes trial on hold

Zafgen Inc said on Monday the U.S. Food and Drug Administration (FDA) had placed a clinical hold on the investigational new drug application for a trial of its experimental diabetes drug.

Zafgen nets $56.5mm via FOPO

Zafgen Inc. (therapies for complex metabolic diseases) netted $56.4mm through a follow-on public offering of 8mm common shares at $7.50 each. The company will use some of the proceeds for ongoing deve...

FDA Halts Clinical Test of Zafgen Diabetes Drug, Stock Price Tumbles

The FDA has ordered Zafgen to suspend a mid-stage study testing its experimental diabetes drug, an apparent precautionary move. A clinical hold halts patient enrollment and also stops already enrolled...

Drugs and Medications [0 Results]


PubMed Articles [0 Results]


Clinical Trials [0 Results]


Companies [1 Associated Companies listed on BioPortfolio]

Zafgen, Inc.

Zafgen is pioneering novel obesity therapeutics that directly target fat metabolism to help the body regain and sustain a lean, healthy state. The company’s approach focuses ...

More Information about "Zafgen, Inc." on BioPortfolio

We have published hundreds of Zafgen, Inc. news stories on BioPortfolio along with dozens of Zafgen, Inc. Clinical Trials and PubMed Articles about Zafgen, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Zafgen, Inc. Companies in our database. You can also find out about relevant Zafgen, Inc. Drugs and Medications on this site too.

Quick Search


Relevant Topics

Obesity is the condition in which excess fat has accumulated in the body (mostly in subcutaneous tissues). clinical obesity is considered to be present when a person has a BMI of over 30 (Oxford Dictionary of Medicine). It is becoming increasing common i...

Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Clincial Trials
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...

Corporate Database Quicklinks

Searches Linking to this Company Record