Dermatitis Research

17:54 EST 22nd January 2019 | BioPortfolio

Air pollution and atopic eczema : Systematic review of findings from environmental epidemiological studies.

Among the many risk factors for the development of atopic eczema (AE), the influence of air pollution has recently been discussed more often. A systematic review about this topic however is lacking.

Kaposi varicelliform eruption induced by methotrexate in an adult atopic dermatitis patient.

Radiation dermatitis with foreign body reaction clinically mimics a cutaneous metastasis from breast cancer.

Hesperidin inhibits keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis via the IRS-1/ERK1/2 pathway.

To evaluate the therapeutic benefits of Hesperidin (Hes) using an imiquimod (IMQ)-induced psoriasis-like mouse model and human immortalized keratinocytes (HaCaT) cells stimulated with lipopolysaccharide (LPS).

Common Neonatal Rashes.

Skin eruptions are commonly encountered in the neonatal and infant period and can be a source of concern for providers and parents alike. We present a brief, clinically focused discussion on topics commonly encountered by the pediatrician with a focus on pearls of knowledge to help distinguish diseases from one another and from more serious conditions. We review miliaria, transient neonatal pustul...

Low amount of formaldehyde in topical medication and cosmetics: is it clinically relevant?

It is difficult for the patients allergic to formaldehyde to totally avoid contact with products containing it as its presence cannot be determined from the ingredient labelling with certainty (1). The aim of this study was to investigate whether formaldehyde could be detected in topical medicines and eye cosmetics when there was no labelled presence of formaldehyde or formaldehyde-releasers. This...

Cinnamon-Induced airborne occupational allergic contact dermatitis in a baker: severe flare-up during patch testing.

Cinnamon (cassia) is a well known but rarely reported cause of occupational allergic contact dermatitis (OACD) in bakers, presenting almost exclusively with hand eczema (1-6). There is only one reported case of airborne OACD from cinnamon in bakers (2). Herein, a rare case of cinnamon-induced airborne OACD is presented in a baker who reacted with a severe flare-up during patch testing. This articl...

Methylisothiazolinone allergic contact dermatitis: assessment of relapses in 139 patients after avoidance advice.

Methylisothiazolinone (MI) is a preservative responsible for an epidemic of allergic contact dermatitis (ACD). Few studies have been published on the prognosis of patients with MI-induced ACD.

Allergic contact dermatitis caused by isopropyl methylphenol, a new hapten.

Isopropyl methylphenol (synonym: o-cymen-5-ol, Biosol; CAS no. 3228-02-2) (Fig. 1) is used as anti-mold and general anti-microbial agent, as preservative, and as antioxidant. It is found in many pharmaceuticals, including over-the-counter (OTC) drugs; quasi-drugs; and cosmetics because it non irritating to the skin and considered not to be a sensitizer . However, three cases of allergic contact de...

Short exposures and glove protection from (meth)acrylates in nail beauticians - thoughts on a rising concern.

Allergic contact dermatitis (ACD) from (meth)acrylates in nail aesthetics is a rising concern, namely in the occupational setting (1)(2). Some technicians may have to abandon the job, as allergen avoidance is difficult (3). Aiming to evaluate the capacity of gloves to protect from occupational ACD we performed patch tests with glove fragments placed between the allergens and patients' skin for dif...

Protein contact dermatitis by flours in a pastry chef.

Protein contact dermatitis is a chronic, recurring dermatitis triggered by type I hypersensitivity to protein allergen . We report a case caused by flours in a pastry chef. This article is protected by copyright. All rights reserved.

Inhibitory checkpoint receptors control CD8+ resident memory T cells to prevent skin allergy.

Tissue-resident memory T cells (Trm) are detrimental in numerous chronic inflammatory diseases, including allergic contact dermatitis (ACD).

Atopic dermatitis in US adults: from population to healthcare utilization.

Little is known about the predictors of healthcare utilization among US adults with atopic dermatitis (AD).

Prenatal perfluorooctanoic acid exposure and glutathione s-transferase T1/M1 genotypes and their association with atopic dermatitis at 2 years of age.

Perfluoroalkyl substance (PFAS) exposure was found associated with atopic diseases. Atopic dermatitis (AD) is a childhood skin disorder. However, the effect of interaction between PFASs and glutathione S-transferase (GST) T1/M1 genotype on AD remains unclear.

Estimating causal associations of atopic dermatitis with depression using the propensity score method: an analysis of Korea Community Health Survey data, 2010-2013.

Numerous studies have reported associations between atopic dermatitis (AD) and depression, but the causal relationship between the 2 diseases has not been established. Therefore, this study used the propensity score method to investigate whether there was a positive causal effect of AD on depression in 16 regions (cities and provinces) in Korea.

The Rise in Atopic Dermatitis in Young Children: What Is the Explanation?

Incidence Trends of Atopic Dermatitis in Infancy and Early Childhood in a Nationwide Prescription Registry Study in Norway.

With increasing prevalence of atopic dermatitis (AD) and its manifestation in most countries, together with the supporting evidence of the progression to other atopic phenotypes, AD has developed into a worldwide public health concern. The presence of the disease of has increased since the 1950s, but some recent studies suggest a stationary or decreasing trend.

Atopy and Sensitization to Allergens Known to Cause Systemic Contact Dermatitis.

Atopic dermatitis (AD) associated with respiratory atopy may represent a form of systemic contact dermatitis (SCD), whereby AD flares after ingestion or inhalation of allergens.

Allergic Reaction to Red Cosmetic Lip Tattoo Treated With Hydroxychloroquine.

Atopic dermatitis is an IL-13 dominant disease with greater molecular heterogeneity compared to psoriasis.

Atopic dermatitis (AD) affects up to 20% of children and adults worldwide. To gain a deeper understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic study of AD with deeply-sequenced RNA-seq samples using long (126) paired-end reads. In addition to the comparisons against previous transcriptomic studies, we conducted in-depth analysis to obtain a high-resolution view o...

The role of emollients in atopic dermatitis in children.

Atopic dermatitis is a chronic inflammatory disease characterized by recurrent flares, intense itching, erythema, dry skin resulting from skin barrier defects, and staphylococcal infections. Multiple factors may affect the skin`s normal barrier function, including filaggrin gene mutations, immune dysregulation, altered skin microbiome, altered lipids in stratum corneum, or deficiency of antimicrob...

IgE-specific immunoadsorption: New treatment option for severe refractory atopic dermatitis.

Effect of dupilumab on atopic manifestations in patients treated for atopic dermatitis in real life practice.

Dupilumab has demonstrated efficacy in atopic dermatitis (AD) , asthma , perennial allergic rhinitis and chronic sinusitis . The objectives of this prospective observational, single-centre study were to assess 1) dupilumab efficacy in real-life practice and 2) the evolution of atopic co-morbidities and specific immunoglobulin E (IgE) levels during dupilumab treatment. This article is protected by ...

Demographics, health care utilization, and drug use in children and adults with atopic dermatitis in Denmark: a population-based cross-sectional study.

Atopic dermatitis (AD) is a common inflammatory skin condition. While previous publications have examined health care expenses, large data regarding patient demographics, health care use and drug prescriptions are limited.

HIDRAdisk: validation of an innovative visual tool to assess the burden of hidradenitis suppurativa.

Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses, and fistulas located in apocrine gland-bearing body sites. The negative impact of HS on patient's quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis and atopic eczema, and its improvement is an important ...

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