22:50 EDT 20th August 2019 | BioPortfolio

Diabetes is a lifelong condition that causes a person's blood sugar level to become too high.

The two main types of diabetes are:

  • type 1 diabetes
  • type 2 diabetes

In the UK, diabetes affects approximately 2.9 million people. There are also thought to be around 850,000 people with undiagnosed diabetes.

Symptoms of diabetes

The main symptoms of diabetes are:

  • feeling very thirsty
  • urinating frequently, particularly at night
  • feeling very tired
  • weight loss and loss of muscle bulk

Type 1 diabetes can develop quickly, over weeks or even days.
Many people have type 2 diabetes for years without realising because early symptoms tend to be general.

Diabetes is characterized by high blood glucose levels, resulting from a problem with Insulin (which is the natural compound that regulates glucose storage). In Type 1 diabetes, no insulin is produced at all because the insulin-producing cells in the pancreas have been destroyed.  This type of diabetes is always treated with insulin injections.

In Type 2, Insulin is produced, but there is either insufficient amounts or it does not work effectively. This type of diabetes is treated with lifestyle changes, following a healthy balanced diet, increasing physical activity, and losing weight if needed. Some people may need medications and/or insulin injections to achieve normal blood glucose levels. Risk factors for Type 2 Diabetes include family history, obesity, hypertension, previous CVD, PCO and severe mental health problems.

It is very important to treat diabetes, and maintain scientific research into this disease because of the complications that Diabetes can cause;  cardiovascular disease, retinopathy, neuropathy, nephropathy, hypoglycaemia, diabetic ketoacidosis or hyperosmolar hyperglycaemic state (HHS).

Top anti-diabetic products worldwide based on market share in 2013 and 2020 (in million U.S. dollars)

Top anti-diabetic products worldwide based on market share in 2013 and 2020
  2013 2020
Lantus (Sanofi) 19.8 14.9
Januvia/Janumet (Merck & Co, Daewoong) 15.2 10.0
NovoRapid (Novo Nordisk) 7.8 6.4
Humalog (Eli Lilly) 6.8 4.2
Victoza (Novo Nordisk) 5.4 6.5

Published by Evaluate
Publication date June 2014
Original source EvaluatePharma - World Preview 2014, Outlook to 2020, page 20 


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