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End-stage kidney disease is the complete or almost complete failure of the kidneys to work. The kidneys remove waste and excess water from the body.
End-stage kidney disease (ESRD) is when the kidneys are no longer able to work at a level needed for day-to-day life.
The most common causes of ESRD in the U.S. are diabetes and high blood pressure. These conditions can affect your kidneys.
ESRD almost always comes after chronic kidney disease. The kidneys may slowly stop working over 10 - 20 years before end-stage disease results.