Joint Disorders Research

15:16 EST 22nd February 2019 | BioPortfolio

Thyroid disorders in Brazil: the contribution of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Thyroid disorders are common diseases, both in Brazil and worldwide. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a prospective cohort study that investigates cardiovascular diseases, diabetes, and associated factors, including non-classical cardiovascular risk factors such as thyroid function. Thyroid function was classified according to thyrotropin stimulating hormone (TSH),...

Hypertensive disorders of pregnancy and peripartum cardiomyopathy: A nationwide cohort study.

Peripartum cardiomyopathy (PPCM) is a serious cardiac disorder occurring late in pregnancy or early in the postpartum period. We examined associations between hypertensive disorders of pregnancy (HDP: preeclampsia and gestational hypertension) and PPCM, accounting for other pregnancy-related risk factors for PPCM.

About a case of gender dysphoria.

The concept of gender dysphoria is used to designate the dissatisfaction resulting from the conflict between gender identity and gender assigned at birth (genetic, gonadal, genital and morphological). The most frequently encountered psychopathologies include depressive disorders, anxiety, substance abuse, disorders of the personality, and they present a suicide attempt rate of 19 to 25%. Being a m...

Lost objects: The territory of study and action of Psychiatry.

The aim of this paper is to discuss about some key issues concerning psychiatry. What really does a psychiatrist nowadays? What kind of disorder does he treat? Why psychiatry keeps itself apart from other specialties and within its own autonomous field? Having in mind the differences between the mental disorders, can we consider that the same semiological elements are appropriate for all of them o...

In vivo prediction of temporomandibular joint disc thickness and position changes for different jaw positions.

Temporomandibular joint disorders (TMD) are common dysfunctions of the masticatory region and are often linked to dislocation or changes of the temporomandibular joint (TMJ) disc. Magnetic resonance imaging (MRI) is the gold standard for TMJ imaging but standard clinical sequences do not deliver a sufficient resolution and contrast for the creation of detailed meshes of the TMJ disc. Additionally,...

Erratum to: Automatic quantification of bone marrow edema on MRI of the wrist in patients with early arthritis: A feasibility study (Magn Reson Med. 2018; 79:1127-1134).

Alterations in Synovial Fluid Biomarker Levels in Knees With Meniscal Injury as Compared With Asymptomatic Contralateral Knees.

Changes in the joint microenvironment after an injury to the articular surface of the knee have been implicated in the pathogenesis of osteoarthritis. While prior studies focused on changes in this microenvironment after anterior cruciate ligament ruptures, few have explored the biomarker changes that occur in the setting of meniscal injuries.

A Nationwide Analysis of Preoperative Planning on Operative Times and Postoperative Complications in Total Knee Arthroplasty.

Compared with nonelective total knee arthroplasties (TKAs), elective procedures have more time for preoperative planning, which allows for potentially improved patient optimization, risk factor modification, and patient education. The purpose of this study was to (1) determine nationwide trends in operative times and (2) evaluate associations between surgery type, elective or nonelective, with res...

Ultrasound and clinical features of hip involvement in patients with gout.

To investigate the prevalence of the ultrasound findings indicative of monosodium urate crystal deposits at the hip joint in patients with gout and to explore the association between the ultrasound findings and the clinical and serological features.

The influence of attachment style and relationship quality on quality of life and psychological distress in carers of people with epileptic and nonepileptic seizures.

Seizure disorders affect not only the individual living with seizures, but also those caring for them. Carer-patient relationships may be influenced by, and have an influence on, some aspects of living with seizure disorders - with potentially different interactions seen in epilepsy and psychogenic nonepileptic seizures (PNES).

Relationships between Quadriceps Tendon Elasticity and Knee Flexion Angle in Young Healthy Adults.

Although tendon elasticity by elastography is useful for diagnosing tendon disorders and planning rehabilitation regimens of the tendon, there are few reports on the quadriceps tendon. Moreover, relationships between the quadriceps tendon elasticity and knee angle have not been investigated. The purpose of this study was to clarify the relationship between quadriceps tendon elasticity and knee fle...

Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.

Longevity is determined by a number of factors, including genetic, environmental and lifestyle factors. A major factor affecting longevity is the development of degenerative disorders such as cardiovascular disease, diabetes, kidney disease and liver disease, particularly where these occur as co-morbidities. In this article, we review the potential role of supplementation with coenzyme Q10 (CoQ10)...

Phosphorus Concentration in Knee Joint Structures of Patients Following Replacement Surgery.

The aim of the study was to assess phosphorus (P) concentration in structures of the knee joint-including the tibial spongy bone, articular cartilage, meniscus, anterior cruciate ligament, and infrapatellar fat pad (Hoffa's fat pad)-of patients following knee joint replacement. The study also aimed to assess the influence of selected biological and environmental factors on P concentration in studi...

A Review of Epigenetics of PTSD in Comorbid Psychiatric Conditions.

Post-traumatic stress disorder (PTSD) is an acquired psychiatric disorder with functionally impairing physiological and psychological symptoms following a traumatic exposure. Genetic, epigenetic, and environmental factors act together to determine both an individual's susceptibility to PTSD and its clinical phenotype. In this literature review, we briefly review the candidate genes that have been ...

Irisin as a new marker for the early diagnosis of low-traumatic fractures in rheumatoid arthritis.

The aim of this study was to study the relationship between serum irisin level and the presence of low-traumatic bone fractures in rheumatoid arthritis (RA) patients. We examined 170 people including 110 RA patients and 60 healthy individuals as comparison group. The serum irisin level was determined with solid-phase enzyme-linked immunosorbent assay using ELISA Irisin test system (BioVendor, cat....

Prevalence of autism spectrum disorders in USA, Europe and Spain: coincidences and discrepancies.

Autism spectrum disorders are a heterogeneous group of disorders that share the presence of two core symptoms: problems in social interaction / communication and the tendency to present restricted interests and repetitive behavior. Over the last years, several epidemiologic studies have been published by different authors in diverse countries, having all of them shown two common characteristics: a...

Functional adaptation and disorders of the autistic spectrum.

Autism spectrum disorders (ASD) are neurodevelopmental disorders that affect social communication and present stereotyped behaviors; 30% of the cases diagnosed with ASD have intellectual disability and 2/3 an intellectual capacity within the norm. Although cognitive ability is related to better functional adaptation, however, the vast majority of people with ASD in adulthood have limited autonomy ...

Clinical Course and Impact of Complex Regional Pain Syndrome Confined to the Knee.

Although complex regional pain syndrome (CRPS) of the knee is comparable to CRPS of the ankle/foot at time of diagnosis, no reports are available concerning the course of knee CRPS. Therefore, this study investigated the clinical course in terms of the symptoms and signs, health-related quality of life (HR-QoL), and work status of patients diagnosed with CRPS of the knee.

Paradoxical Arthritis in Inflammatory Bowel Diasease Patients on Ustekinumab Treatment.

Glycogen synthase kinase-3 inhibitor as a multi-targeting anti-rheumatoid drug.

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that causes swelling, bone erosion, and joint disorder. Patients with RA therefore suffer from pain and physiological disability, and have a decreased quality of life. During the progression of RA, many different types of cells and inflammatory factors influence each other with an important role. A better understanding of the pathol...

Complex regional pain syndrome secondary to everolimus: two cases.

The safest and most efficacious route of tranexamic acid administration in total joint arthroplasty: A systemic review and network meta-analysis.

Blood loss in Total Joint Arthroplasty can be significant and often under-estimated. This study aims to investigate the safety and efficacy of different routes of tranexamic acid (TXA) administration in reducing blood transfusion after Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA). The secondary aim is to find the safest and most efficacious route and dose of TXA.

Test-retest reliability of elbow flexor contraction characteristics with tensiomyography for different elbow joint angles.

Tensiomyography (TMG) has gained popularity as a tool to quantify muscle contractile properties. However, it is unclear whether joint angle and inter-stimulus interval influence the test-retest reliability of TMG. Fifteen participants (13M/2F; 29.5 ± 7.4 y) underwent TMG recording of the biceps brachii (BB) at 10°, 45° and 90° of elbow flexion with 10 and 20 s inter-stimulus rest inter...

The application of pediatric voice handicap index in children with voice disorders.

To access the influence of voice disorders on children's voice-related quality of life through the parental version of pediatric voice handicap index (pVHI). From April 2017 to March 2018, a total of 192 children with voice disorders (dysphonic group) and 111 children without voice disorders (control group) were enrolled in this work. Parents of children in both groups were asked for fill out the...

Abatacept initiation in rheumatoid arthritis and the risk of serious infection: A population-based cohort study.

To assess whether abatacept as initial biologic disease-modifying antirheumatic drug (DMARD) in the treatment of rheumatoid arthritis is associated with an increased risk of serious infections, including bone and joint, gastrointestinal, respiratory tract, skin and soft tissue, and urinary tract, when compared with other biologic DMARDs.

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