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Mental Health Research

05:36 EDT 23rd May 2018 | BioPortfolio

Attention-Deficit/Hyperactivity Disorder Symptoms, Depression Risk, and Quality of Life in Black Pregnant Women.

Experiencing mental health difficulties during pregnancy predicts a variety of quality-of-life (QoL) outcomes for Black women. However, one area of prenatal mental health remains underresearched: attention-deficit/hyperactivity disorder (ADHD). Given the impairments reported by adults with significant symptoms of ADHD and the linkages between depression and ADHD in nonpregnant samples, the current...

Cdk5-mediated Acn/Acinus phosphorylation regulates basal autophagy independently of metabolic stress.

In neurons, autophagy counteracts consequences of aging. It is therefore of interest how basal rates of macroautophagy/autophagy can be controlled independently of metabolic stress. We recently investigated the regulation of basal, starvation-independent autophagy by Acn/Acinus, a multifunctional nuclear protein with proposed roles in apoptosis, alternative RNA splicing, and basal autophagy. We fo...

Assessing the Confidence of Australian Mental Health Practitioners in Delivering Therapy to People With Intellectual Disability.

Research supports the use of psychological therapies among people with mild to moderate intellectual disability (ID). One barrier to people with ID accessing psychological treatments is the confidence of mental health practitioners. This article explores the confidence of Australian clinicians in providing therapy to people with ID. One hundred and fifty-two psychologists and counselors in Austral...

Weight Loss During Atomoxetine Add-on to Clozapine-Responsive Schizophrenia.

Keeping Up with Today's Top Health Law Issues to Avoid a 'Nasty Surprise'.

Just as in fictional television shows and movies, reality in the healthcare industry sometimes includes complications, disruptions, glitches, and nasty surprises. This article reviews several important legal topics, including emergency planning, privacy, fraud, public health, and ethics, to name only a few. Healthcare administrators are not expected to be attorneys or compliance officers, but they...

The dysfunction of processing emotional faces in schizophrenia revealed by expression-related visual mismatch negativity.

To investigate the emotional face processing in patients with schizophrenia, the preattentive automatic processing of emotional faces in individuals with schizophrenia was compared with that of age-matched healthy control group as indexed by the expressional mismatch negativity (EMMN) elicited by facial expressions. Compared with neutral faces as standard stimuli, deviant emotional faces elicited ...

Organizational Supports for Research Evidence Use in State Public Health Agencies: A Latent Class Analysis.

Use of research evidence in public health decision making can be affected by organizational supports. Study objectives are to identify patterns of organizational supports and explore associations with research evidence use for job tasks among public health practitioners.

The Therapeutic Relationship: Enhancing Referrals.

This article focuses on the ways rehabilitation nurses use the therapeutic relationship to lessen barriers some veterans experience when a referral to mental health treatment is recommended.

Measurement agreement of the self-administered questionnaire of the Belgian Health Interview Survey: Paper-and-pencil versus web-based mode.

Before organizing mixed-mode data collection for the self-administered questionnaire of the Belgian Health Interview Survey, measurement effects between the paper-and-pencil and the web-based questionnaire were evaluated. A two-period cross-over study was organized with a sample of 149 employees of two Belgian research institutes (age range 22-62 years, 72% female). Measurement agreement was asses...

Simulation of dyslexia. How literacy and cognitive skills can help distinguish college students with dyslexia from malingerers.

Academic accommodations associated with a diagnosis of dyslexia might be incentives for college students without reading or spelling difficulties to feign dyslexia and obtain the diagnosis unfairly. In the current study we examined malingering practices by comparing the performance of college students instructed to malinger dyslexia (n = 28) to that of students actually diagnosed with dyslexia (n ...

Discrimination and distress among Afghan refugees in northern California: The moderating role of pre- and post-migration factors.

This study investigates the effect of perceived discrimination on the mental health of Afghan refugees, and secondly, tests the distress moderating effects of pre-migration traumatic experiences and post-resettlement adjustment factors. In a cross-sectional design, 259 Afghans completed surveys assessing perceived discrimination and a number of other factors using scales developed through inductiv...

Validation of the Refugee Health Screener-15 for the assessment of perinatal depression among Karen and Burmese women on the Thai-Myanmar border.

Perinatal depression is common, and left untreated can have significant and long-lasting consequences for women, their children and their families. Migrant women are at particular risk of perinatal depression as a result of a multitude of stressors experienced before, during and after migration. Identification of perinatal depression among migrant women-particularly those living in low- and middle...

True technology-enabled mental health care: when will we trust the computers and robots?

Changes in behavioural parameters, oxidative stress and neurotrophins in the brain of adult offspring induced to an animal model of schizophrenia: The effects of FA deficient or FA supplemented diet during the neurodevelopmental phase.

A deficiency of maternal folic acid (FA) can compromise the function and development of the brain, and may produce a susceptibility to diseases such as schizophrenia (SZ) in the later life of offspring. The aim of this study was to evaluate the effects of both FA deficient and FA supplemented diets during gestation and lactation on behavioural parameters, the markers of oxidative stress and neurot...

Targeting central β2 receptors ameliorates streptozotocin-induced neuroinflammation via inhibition of glycogen synthase kinase3 pathway in mice.

Alzheimer's disease (AD) is portrayed by progressive cognitive decline and pathological deposition of amyloid plaques as well as neurofibrillary tangles. Most of AD cases are sporadic, resulting from overlap of various environmental and genetic factors. Intra-cerebroventricular injection of streptozotocin (STZ) leads to insulin resistance brain state accompanied by memory decline, oxidative stress...

Monosodium glutamate induced nociception and oxidative stress dependent on time of administration, age of rats and susceptibility of spinal cord and brain regions.

Monosodium glutamate (MSG), a food flavor enhancer used worldwide, has been studied because it may cause neurotoxicity, which is associated with oxidative stress. The aim of this study was to investigate whether spinal cord and brain regions are affected by oxidative stress and the temporal profile of nociceptive responses induced by MSG in newborn and adult rats. The newborn (post natal day, PND ...

Factors affecting gene expression and activity of heme- and manganese-dependent catalases in Lactobacillus casei strains.

Catalases reduce oxidative stress by degrading hydrogen peroxide to molecular oxygen and water. The presence of heme-dependent or manganese-dependent catalases was observed for a long time in lactic acid bacteria (LAB) but, to date, knowledge on the factors affecting gene expression and enzymatic functionality are limited to a very few strains. In this study, the effect of atmosphere of incubation...

Memory retrieval of everyday information under stress.

Psychosocial stress is known to crucially influence learning and memory processes. Several studies have already shown an impairing effect of elevated cortisol concentrations on memory retrieval. These studies mainly used learning material consisting of stimuli with a limited ecological validity. When using material with a social contextual component or with educational relevant material both impai...

Recurrent truncal dystonia (Pisa syndrome) due to donepezil - A case report.

Meta-analysis of FOXP2 rs10447760 polymorphism with schizophrenia.

Proportion and reasons for medication non-compliance among schizophrenics: A cross-sectional observation in a tertiary care hospital of Bangladesh.

Is death anxiety more closely linked with optimism or pessimism among older adults?

The purpose of this study was to investigate whether death anxiety is more closely linked with optimism or pessimism among older adults. Participants consisted of community-dwelling older adults (N = 253; 73.1% female) in the southern U.S. Both optimism and pessimism demonstrated a bivariate association with death anxiety; however, when considering optimism and pessimism together-and after con...

Maternal hypothalamus-pituitary-adrenal (HPA) system activity and stress during pregnancy: Effects on gestational age and infant's anthropometric measures at birth.

Prenatal maternal stress might be a risk for the developing fetus and may have long-lasting effects on child and adult vulnerability to somatic and psychiatric disease. Over-exposure of the unborn to excess glucocorticoids and subsequent alteration of fetal development is hypothesized to be one of the key mechanisms linking prenatal stress with negative child outcome.

ω-3 and folic acid act against depressive-like behavior and oxidative damage in the brain of rats subjected to early- or late-life stress.

To investigate the antidepressant and antioxidant effects of omega-3, folic acid and n-acetylcysteine (NAC) in rats which were subjected to early or late life stress.

H-NMR and UPLC-MS metabolomics: Functional tools for exploring chemotypic variation in Sceletium tortuosum from two provinces in South Africa.

Sceletium tortuosum (Aizoaceae) is widely recognised for the treatment of stress, anxiety and depression, as well as for obsessive compulsive disorders. A comprehensive intraspecies chemotypic variation study, using samples harvested from two distinct regions of South Africa, was done using both proton nuclear magnetic resonance (H-NMR) spectroscopy of methanol extracts (N = 145) and ultra per...

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