MiniMed 530G with Enlite Research

23:50 EST 20th January 2020 | BioPortfolio

Insulin pumps use in Greece: efficacy and safety data from 140 patients with type 1 diabetes mellitus.

The aim of this study was to investigate the efficacy and safety of continuous subcutaneous insulin infusion (CSII) regarding glycaemic control and quality of life in patients with type 1 diabetes mellitus (T1DM), who were previously treated with a multiple daily injections (MDI).

Successful post-transition engagement can be predicted at the time of transition in type 1 diabetes.

Concerns About the Use of Metformin as a First-Line Agent to Slow the Progression of Chronic Kidney Disease in Diabetes.

The association between health care coverage and prevalence of cardiovascular diseases and diabetes over a 10-year period.

Persons without health care coverage have poorer health outcomes. We investigated the association between health care coverage and trends in the prevalence of cardiovascular disease (CVD) and diabetes pre- and post-Affordable Care Act (ACA) periods. Using data from 3,824,678 surveyed adults in the Behavioral Risk Factor Surveillance System survey from 2007 - 2016, we calculated the yearly prevalen...

Impact of Diabetes and Low Body Mass Index on Tuberculosis Treatment Outcomes.

Diabetes was identified as a tuberculosis (TB) risk factor mostly in retrospective studies with limited assessment of metabolic variables. The prospective Effects of Diabetes on Tuberculosis Severity study compared adults with pulmonary TB in Chennai, India, who were classified as having diabetes or normal glucose tolerance at enrollment.

Infertility, gravidity, and risk of diabetes among high-risk women in the Diabetes Prevention Program Outcomes Study.

The extent to which infertility and pregnancy independently increase risk of diabetes and subclinical atherosclerosis is not known.

Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry.

Cardiovascular disease (CVD) is a major cause of mortality in adults with type 1 diabetes.

Differential Survival Impact of Diabetes Mellitus on Hepatocellular Carcinoma: Role of Staging Determinants.

Diabetes mellitus (DM) is common in patients with hepatocellular carcinoma (HCC) and may impact survival. Very few studies focused on the influence of DM in different clinical scenarios. We evaluated the prognostic impact of DM on HCC patients stratified by liver dysfunction, Milan criteria, and performance status defined in the Barcelona Clínic Liver Cancer staging parameters.

Metformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus Via the Methylglyoxal Pathway.

The aim of our study was to determine the effect of metformin administration on juvenile type 1 diabetes mellitus and atherosclerosis in apolipoprotein E null (ApoE) mice and to explore the mechanism involved.

External validation and clinical utility of prognostic prediction models for gestational diabetes mellitus: a prospective cohort study.

We performed an independent validation study of all published first trimester prediction models, containing non-invasive predictors, for the risk of gestational diabetes mellitus (GDM). Furthermore, the clinical potential of the best performing models was evaluated.

Seasonal variations in incidence and maternal-fetal outcomes of gestational diabetes.

To determine whether the neonatal and delivery outcomes of gestational diabetes vary seasonally in the context of a relatively cool temperate climate.

Item reduction of the 39-item Rotterdam Diabetic Foot Study Test Battery using decision tree modeling.

Pedal sensory loss due to diabetes-related neuropathy can be graded by testing static- and moving two-point discrimination (S2PD, M2PD), static one-point discrimination (S1PD, e.g. 10 g monofilament) and vibration sense, and are included in the Rotterdam Diabetic Foot Study Test Battery. The aim of this study is to investigate if decision tree modeling is able to reduce the number of tests needed ...

Efficacy of Exenatide and Insulin Glargine on Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus.

The aim of this study was to investigate the efficacy of exenatide and insulin glargine in patients with newly diagnosed type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD).

Simvastatin alleviated diabetes mellitus-induced erectile dysfunction in rats by enhancing AMPK pathway-induced autophagy.

Diabetes mellitus-induced erectile dysfunction (DMED) is a common diabetic complication, and new therapeutics and the pathogenesis of DMED need to be investigated.

Anti-diabetic activity of crude polysaccharide and rhamnose-enriched polysaccharide from G. lithophila on Streptozotocin (STZ)-induced in Wistar rats.

The aim of the present study was to elucidate the anti-diabetic effects of the crude polysaccharide and rhamnose-enriched polysaccharide derived from G. lithophila on streptozotocin (STZ)-induced diabetic Wistar rats. Treatment with crude polysaccharide and rhamnose-enriched polysaccharide showed increases in body weight and pancreatic insulin levels and a decrease in blood glucose levels compared...

Very Low and Higher Carbohydrate Diets Promote Differential Appetite Responses in Adults with Type 2 Diabetes: A Randomized Trial.

Effects of very low carbohydrate (VLC) diets on appetite response in individuals with type 2 diabetes remain unclear.

Hypovascular pancreas head adenocarcinoma: CT texture analysis for assessment of resection margin status and high-risk features.

To determine if CT texture analysis features are associated with hypovascular pancreas head adenocarcinoma (PHA) postoperative margin status, nodal status, grade, lymphovascular invasion (LVI), and perineural invasion (PNI).

10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes.

The aim of this study was to evaluate the 10-day initiation protocol for MiniMed 670G hybrid closed-loop (HCL) system in individuals with type 1 diabetes on multiple daily injection (MDI) in achieving desirable glycemic control.

Cost of Managing Type 2 Diabetes Before and After Initiating Dipeptidyl Peptidase 4 Inhibitor Treatment: A Longitudinal Study Using a French Public Health Insurance Database.

Diabetes is a growing epidemic that imposes a substantial economic burden on healthcare systems. This study aimed to evaluate the cost of managing type 2 diabetes (T2D) with dipeptidyl peptidase 4 inhibitors (DPP4Is) using real-world data.

Clinical profile at diagnosis with youth-onset type 1 and type 2 diabetes in two pediatric diabetes registries: SEARCH (United States) and YDR (India).

Over the last decades, diabetes in youth has increased in both India and the U.S., along with the burden of long-term complications and healthcare costs. However, there are limited standardized population-based data in contemporary youth cohorts for comparison of clinical and demographic characteristics of diabetes for both type 1 (T1D) and type 2 (T2D).

A clinical study on the effectiveness of biopsychosocial-spiritual treatment approach for diabetic patients.

The purpose of conducting this study was to examine the effectiveness of a biopsychosocial-spiritual model in the management of symptoms of a diabetic patient. A 38-year-old female diagnosed with diabetes complained of bouts of sadness and fatigue, a reduced interaction with others, difficulty in falling asleep, felt irritable and experienced severe pain in the joints. The Siddique Shah Depression...


This communication is an interesting and off-beat take on the concept of theranostics, as applied to diabetes care. It proposes the use of the term diabeto-theranostics, to define the combined use of diagnostic and therapeutic modalities, so as to create individualized or personalized treatment strategies in persons with diabetes. Historical examples such as the chlorpropamide challenge test and m...

Handling hearsay in diabetes care.

Hearsay, including e-hearsay, is an unwanted, yet unavoidable, part of modern medical practice. Misinformation creates a barrier for the acceptance of, and adherence to, diabetes management. Modern technology has facilitated the spread of (mis) information. This communication describes the disadvantages of hearsay. It suggests ways for physicians to tackle diabetes hearsay in their patients and co...

The role of α-cells in islet function and glucose homeostasis in health and type 2 diabetes.

Pancreatic α-cells are the major source of glucagon, a hormone that counteracts the hypoglycemic action of insulin and strongly contributes to the correction of acute hypoglycemia. The mechanisms by which glucose controls glucagon secretion are hotly debated, and it is still unclear to what extent this control results from a direct action of glucose on α-cells or is indirectly mediated by β- an...

Difference in sarcopenia prevalence and associated factors according to 2010 and 2018 European consensus (EWGSOP) in elderly patients with type 2 diabetes mellitus.

The aim of this study was to establish the prevalence of sarcopenia and associated factors in elderly patients with type 2 diabetes mellitus (DM) according to 2010 (EWGSOP1) and 2018 (EWGSOP2) European consensus.

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