Nanotechnology Research

12:33 EST 28th January 2020 | BioPortfolio

A novel strategy for glioblastoma treatment combining alpha-cyano-4-hydroxycinnamic acid with cetuximab using nanotechnology-based delivery systems.

Combination therapy that uses multiple drugs against different molecular targets should be considered as interesting alternatives for treating complex diseases such as glioblastoma (GBM). Drugs like alpha-cyano-4-hydroxycinnamic acid (CHC) and the monoclonal antibody cetuximab (CTX) are already explored for their capacity to act against different hallmarks of cancer. Previous reports suggest that ...

Author Correction: Precise targeting of POLR2A as a therapeutic strategy for human triple negative breast cancer.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Catalytic Nucleic Acids: Biochemistry, Chemical Biology, Biosensors, and Nanotechnology.

Since the initial discovery of ribozymes in the early 1980s, catalytic nucleic acids have been used in different areas. Compared with protein enzymes, catalytic nucleic acids are programmable in structure, easy to modify, and more stable especially for DNA. We take a historic view to summarize a few main interdisciplinary areas of research on nucleic acid enzymes that may have broader impacts. Ear...

Advances in Using Nanotechnology Structuring Approaches for Improving Food Packaging.

Recent advances in food packaging materials largely rely on nanotechnology structuring. Owing to several unique properties of nanostructures that are lacking in their bulk forms, the incorporation of nanostructures into packaging materials has greatly improved the performance and enriched the functionalities of these materials. This review focuses on the functions and applications of widely studie...

30 Years of Nanotechnology.

Corrigendum: Copper induced hollow carbon nanospheres by arc discharge method: controlled synthesis and formation mechanism (2016 Nanotechnology 27 335602).

We regret to inform about an error in the above-mentioned paper, i.e., the raw Raman spectrum of copper-carbon DC arc discharge product prepared with 10% of CH4 in the gas mixture of CH4/He as shown in figure 5c. This raw spectrum and its deconvoluted components are replaced. The corresponding text about Raman results is re-described. These errors do not affect the discussion or interpretation of ...

Application of nanotechnology based-biosensors in analysis of wine compounds and control of wine quality and safety: A critical review.

Nanotechnology is one of the most promising future technologies for the food industry. Some of its applications have already been introduced in analytical techniques and food packaging technologies. This review summarizes existing knowledge about the implementation of nanotechnology in wine laboratory procedures. The focus is mainly on recent advancements in the design and development of nanomater...

Perspective: Computational Nanobiosensing.

With the development of nanotechnology, externally manipulable or self-regulatable smart nanosystems can be utilized as effective tools for computational nanobiosensing, where natural computing strategies are exploited for knowledge-aided nanobiosensing.

Thiol-antioxidants interfere with assessing silver nanoparticle cytotoxicity.

Many studies have shown that silver nanoparticles (AgNP) induce oxidative stress, and it is commonly assumed that this is the main mechanism of AgNP cytotoxicity. Most of these studies rely on antioxidants to establish this cause-and-effect relationship; nevertheless, details on how these antioxidants interact with the AgNP are often overlooked. This work aimed to investigate the molecular mechani...

Nanotechnology Based Diagnostics and Therapy for Pathogens- Related Infections in the CNS.

The central nervous system (CNS) encompasses the brain, spinal cord, and nerves, where both brain and spinal cord are safeguarded by the meninges. However, serious bacterial, viral or fungal infection in the brain causes life-threatening diseases such as meningitis. Engineered nanostructures hold great promise for not only in the diagnosis but also for combating microbial drug resistance owing to ...

Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy.

Nanotechnology has been the latest approach for diagnosis and treatment of cancer, which opens up a new alternative therapeutic drug delivery option to treat disease. Nanoparticles (NPs) display a broad role in cancer diagnosis and has various advantages over the other conventional chemotherapeutic drug delivery. NPs possess more specific and efficient drug delivery to the targeted tissue, cell, o...

Nanotechnology in regenerative ophthalmology.

In recent years, regenerative medicine is gaining momentum and is giving hopes for restoring function of diseased, damaged, and aged tissues and organs and nanotechnology is serving as a catalyst. In the ophthalmology field, various types of allogenic and autologous stem cells have been investigated to treat some ocular diseases due to age-related macular degeneration, glaucoma, retinitis pigmento...

New Patent on Electrospinning for Increasing of Rutin Loading in Nanofibers.

The electrospinning and the bubble electrospinning provide facile ways for fabrication of functional nanofibers by incorporating rutin/hydroxypropyl-β-cyclodextrin inclusion complex (RT/HP-β-CD-IC) in polyvinyl alcohol (PVA).

Emerging neuromorphic devices.

Not applicable at Outline stage.

Progress of Electrospray and Electrospinning in Energy Applications.

In the promotion of energy strategies to address the global energy crisis, nanotechnology has been successfully used to generate novel energy materials with excellent characteristics, such as high specific surface area, good flexibility and large porosity. Among the various methods for fabricating nanoscale materials, electrospray and electrospinning technologies have unlocked low-cost, facile and...

Influence of Albumin in the Microfluidic Synthesis of PEG-PLGA Nanoparticles.

A key challenge in manufacturing of polymeric colloids is producing nanoparticles with good batch-to-batch consistency.

Label-free liquid biopsy based on blood circulating DNA detection using SERS-based nanotechnology for nasopharyngeal cancer screening.

Development of a sensitive, rapid and easy-to-use liquid biopsy method is of imperative clinical value for point-of-care caner diagnostics. Here, a label-free and modification-free nanotechnology based on surface-enhanced Raman spectroscopy (SERS) was employed for DNA analysis. Using the SERS signals of phosphate backbone as internal standard, quantitative detection for nucleobases was achieved ev...

Targeting Nanotechnologies for the Treatment of Thrombosis and Cardiovascular Disease.

Thrombosis is characterized by the formation of in vivo blood clots that are localized within arterial or venous blood vessels. These thrombi form beyond the need for physiologically healthy hemostatic responses and can lead to significant medical issues for affected individuals. Unfortunately, the existing standard-of-care therapies for treating thrombosis are systemic in their therapeutic design...

Switching from Conventional to Nano-natural Phytochemicals to Prevent and Treat Cancers: Special Emphasis on Resveratrol.

Natural phytochemicals and their derivatives have been used in medicine since prehistoric times. Natural phytochemicals have potential uses against various disorders, including cancers. However, due to low bioavailability, their success in clinical trials has not been reproduced. Nanotechnology has played a vital role in providing new directions for diagnosis, prevention, and treatment of differen...

The State of Nanorobotics in Medicine.

From ant-man to the Incredible Shrinking Machine, society has long envisioned developing devices tiny enough to enter human cells. Such nanotechnology could revolutionize the diagnosis of diseases like cancer and neurodegeneration, span new methods of precise drug delivery, and even directly repair damaged organs.

Nanotechnology: a reality for diagnosis of HCV infectious disease.

Hepatitis C virus (HCV) is the primary etiologic agent of liver cirrhosis or hepatocellular carcinoma. HCV elevated infection rates are mostly due to the lack of an accurate and accessible screening and diagnosis, especially in low- and middle-income countries. Conventional HCV diagnostic algorithm consists of a serological test followed by a nucleic acid test. This sequence of tests is time consu...

Protective effects of Cer and Ytt Ox NPs and Nan Se on H2O2-induced oxidative stress in pancreatic Beta cells.

Type 1 diabetes mellitus (T1DM) is characterized by the destruction of insulin-producing Beta cells in the pancreas. Researchers hope that islet transplantation will help to patients with IDDM.

Focused-helium-ion-beam blow forming of nanostructures: radiation damage and nanofabrication.

Targeted irradiation of nanostructures by a finely focused ion beam provides routes to improved control of material modification and understanding of the physics of interactions between ion beams and nanomaterials. Here, we studied radiation damage in crystalline diamond and silicon nanostructures using a focused helium ion beam, with the former exhibiting extremely long-range ion propagation and ...

Knowledge about nanotechnology and intention to use nanomaterials: a comparative study among dental students in Norway and Romania.

The introduction of innovative nanotechnologies in medicine and dentistry may initiate a need for curriculum revision at the universities. The aim of this study was to assess dental students' knowledge and attitudes related to nanotechnology. Covariates of students' intention to use nanomaterials in their future dental practice were evaluated using the theory of planned behavior (TPB).

An Innovative Approach to Nano Thiazole-Zn with Promising Physicochemical and Bioactive Properties by Nanoreactor Construction.

Nanotechnology has provided a novel approach for the preparation of a safe and highly effective pesticide formulation. Thiazole-Zn, a widely used bactericide, was successfully prepared at nanoscale by an innovative approach of final synthesis process control. Its plausible formation mechanism based on restricted particle aggregation in a nanoreactor was elucidated. Then in order to assess the appl...

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