Latest "Challenge" News Stories - Page: 20

Tie-Up Moves Kangstem's Novel Stem Cell Therapy Towards Globalization

Helped by a new partnership with Belgium-based MaSTherCell, the South Korean biotech is aiming to initially challenge the European market...   

Cell And Gene Therapies Test New Waters In Pricing And Reimbursement

With the first few cell and gene therapies launched in the US, the challenge of pricing and reimbursement – and...   

Breastfeeding in Germany from a scientific viewpoint

(BfR Federal Institute for Risk Assessment) Is breastfeeding really better? The intense debate on this question has been going on for decades -- and is often controversial and emotionally discussed. Breastfeeding is more than just babies' nutrition. It is associated with physical and psychological changes in both mother and child. The challenge for research is to determine the different effects of...

Sandoz selects finalists in digital tech healthcare access competition

Sandoz has selected three finalists in a competition to use digital technology to increase access to medicines in poorer countries. The generics and biosimilars arm of Novartis has been running its second Healthcare Access Challenge – known as the...

BodyArmor Rejects NAD Ad Claims Decision Following Gatorade Challenge

BA Sports stands by claims comparing BodyArmor SuperDrink to Gatorade and will not pull or change ads as an industry...    

Novartis’ Entresto Faces Challenge From Natco In India

Natco has launched a cut-price version of sacubitril/valsartan (Novartis' Entresto) on the Indian market and is also believed to have...   

FDA Looks To Strengthen, Speed Drug Reviews With Flow Of Quality Data

Lift the burden of paper on drug quality reviews and the pace of innovation is no longer a problem for...    

AbbVie, Genentech Raise New Constitutional Challenge To Inter Partes Review

Firms contend that IPR should not apply to patents filed before America Invents Act was enacted, objecting to IPR decisions...    

Impressive Responses for Patients With NTRK Fusion Tumors

New data continue to show impressive responses to larotrectinib in patients with tumors that harbor the NTRK gene fusion, but finding such patients could be a challenge. Medscape Medical News

Report Makes the Case for ID Physician Leadership in Cutting Unnecessary Antimicrobial Use

A paper published in Clinical Infectious Diseases today describes how infectious diseases physicians are uniquely positioned to lead programs guiding the use of antimicrobial medicines. The increasingly critical challenge of antimicrobial resistance threatens both individual and public health. Multiple studies examining infectious diseases

Hospitals Work to Improve Procedures Designed to Protect Staff and Patients From Harm

Hospitals are looking for new and better ways to protect staff and patients, both from intruders who mean harm, and patients or family members who become aggressive and agitated. However, defending against active assailants presents the greatest challenge, as hospitals and EDs strive to remain open and welcoming to the communities they serve.

MKSAP: 36-year-old woman with refractory constipation

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 36-year-old woman is evaluated for a 12-year history of refractory constipation. Her symptoms began after a difficult childbirth. She has constipation marked by straining, bloating, and a constant sensation of incomplete emptying. She sometimes has 4 or more days between […]

Study: 'Post-normal' science requires unorthodox communication strategies

Proposals to fight malaria by 'driving' genes that slow its spread through mosquitoes is a high-risk, high-reward technology that presents a challenge to science journalists, according to a new report aimed at stimulating a fruitful, realistic public discussion of 'post-normal' science and technology.

MKSAP: 48-year-old man with a 4-week history of heartburn

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 48-year-old man is evaluated for a 4-week history of heartburn that awakens him at night. The symptoms occur about three times per week. He has been taking over-the-counter antacids with incomplete relief. Food triggers include coffee and spicy foods. He […]

Medicare's CAR-T Panel Underscores Hurdles For PROs – And FDA/CMS Collaboration

MEDCAC meeting demonstrates complexity of patient-reported outcomes and place for PROs in regulatory decision-making compared to coverage.   

Schizophrenia Drug Discovery Has Scared Off Many Researchers, But This Group Is Taking On Challenge

A lack of understanding about the disease's physiology makes creating new medicines difficult. “So we hope to revolutionize the way schizophrenics are being treated. … We hope to give these people their lives back," Remy Luthringer, CEO of Boston-based Minerva Neurosciences, tells Stat. In other biotech and pharmaceutical news: companies thrive in Minnesota. And production resumes at a trouble...

Advaxis Stumbles Further As Amgen Exits Early-Stage Cancer Immunotherapy Pact

Troubled by a clinical hold for another program, Advaxis now regains all rights to ADXS-NEO, a personalized immunotherapy in Phase...   

Advocates Press For US FDA Rare Disease Center Of Excellence

Attorneys' proposal aims to better connect dispersed rare disease expertise within FDA's drug, biologic, and device centers through more leadership...   

MKSAP: 57-year-old man with type 2 diabetes mellitus

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 57-year-old man with a 15-year history of type 2 diabetes mellitus is evaluated for bilateral burning sensation in his feet for the last 6 to 12 months. The sensation worsens at night. His HbA1c levels have remained less than 7.0% […]

Let’s beat it! £30 million research funding award launches for breakthrough in heart disease

The British Heart Foundation has launched a unique research funding award, the Big Beat Challenge, aimed at bringing together world-leading researchers and innovators to identify and solve any of the biggest problems in heart and circulatory disease

Fungi cause brain infection and memory impairment in mice

How pneumococci challenge our immune system

(Karolinska Institutet) Pneumococci are the most common cause of respiratory tract infections, such as otitis and sinusitis, as well as of severe infections like pneumonia and meningitis. A new study from Karolinska Institutet in Sweden published in Nature Microbiology shows how the bacteria can inhibit immune cell reaction and survive inside cells to give rise to pneumonia.

Protein involved in nematode stress response identified

(University of Illinois College of Agricultural, Consumer and Environmental Sciences) When humans experience stress, their inner turmoil may not be apparent to an outside observer. But many animals deal with stressful circumstances -- overcrowded conditions, not enough food -- by completely remodeling their bodies. These stress-induced forms, whether they offer a protective covering or more camouf...

Mission: Possible -- mapping dangerous terrain

(University of Houston) Ensuring military forces have up-to-date information about a potentially hostile region offers obvious advantages, but current methods for doing that -- especially along shorelines, where underwater mines and other hazards can pose serious risks -- all have drawbacks. Engineers from the University of Houston are addressing the challenge as part of a $1 million project led b...

European Patent Office Upholds Gilead’s Sofosbuvir Patent

A challenge brought to the European Patent Office that sought to open the door to generic competition to Gilead’s hepatitis...