Latest Biotechnology, Pharmaceutical and Healthcare News from JAMA

00:40 EDT 21st September 2019 | BioPortfolio

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Showing News Articles 1–25 of 317 from JAMA

Thursday 19th September 2019

The Advancing American Kidney Health Executive Order—A Chance to Enhance Organ Donation

This Viewpoint uses provisions in President Trump’s 2019 American Kidney Health Executive order calling for an increase in access to kidney transplantation to discuss strategies to increase deceased and living donor pools, improve allocation of organs from higher-risk donors, and support the long-term medical needs of living donors.

Value-Based Purchasing and Physician Professionalism

This Viewpoint discusses the importance of structuring value-based purchasing models around principles of physician professionalism to ensure that measures that lead to more payment are clinically meaningful, do not increase administrative burden, do not displace clinicians’ intrinsic motivation to help patients with financial motivations, and do not incentivize physicians to avoid sicker, more ...

Wednesday 18th September 2019

Sulfonylureas and Cardiovascular Safety—The Final Verdict

As the options for glucose-lowering medications for patients with type 2 diabetes have expanded, the choices for physicians and patients have become more difficult. Owing to a 2008 US Food and Drug Administration mandate, more than 20 randomized, mostly placebo-controlled, cardiovascular outcomes trials (CVOTs) of new glucose-lowering medications have been published in the last 5 years, prompting ...

Metformin or Sulfonylurea Use in Kidney Disease

This cohort study uses data from the National Veterans Health Administration, Medicare, Medicaid, and National Death Index to compare major adverse cardiovascular events among patients with diabetes and reduced kidney function who continued treatment with metformin or sulfonylurea.

Linagliptin vs Glimepiride and Cardiovascular Outcomes in Patients With Type 2 Diabetes

This randomized noninferiority clinical trial examines the effect of treatment with the dipeptidyl peptidase-4 inhibitor linagliptin vs the commonly used sulfonylurea glimepiride on cardiovascular safety in patients with type 2 diabetes and cardiovascular risk factors or established atherosclerotic cardiovascular disease.

Tuesday 17th September 2019

In Hot, Humid Weather, Benefit Health and Environment

This Medical News article discusses a recent study about the effect of fans on relieving the physiological stress of high temperatures.

Finding the Right Words to Stop Cancer Screening in Older Adults

In this Medical News article, experts discuss sensitive ways to tell older adults that they no longer need cancer screening when their life expectancy is less than 10 years.

Sunday 15th September 2019

The Ninth International Congress on Peer Review and Scientific Publication: A Call for Research

The quantity and quality of scientific research have never been greater, but with unprecedented promise comes unprecedented peril. There are better scientific policies and processes, stronger standards for openness and transparency, and innovative technologies to collaborate and publish. However, the rapidly evolving scientific publication ecosystem that facilitates research dissemination also ena...

Prevalence of e-Cigarette Use Among Adults in the United States, 2014-2018

This population epidemiology study uses 2014-2018 data from National Health Interview Surveys to assess trends in prevalence of current and daily e-cigarette use by US adults and to characterize trends by sociodemographic and smoking status among young adults (18-24 years).

Thursday 12th September 2019

Redefining Heart Failure With a Reduced Ejection Fraction

In this Viewpoint, Milton Packer and colleagues argue that reliance on a threshold of LVEF ≤40% to define heart failure with reduced ejection fraction (HFrEF) may exclude patients with impaired systolic function and subnormal LVEF from evidence-based treatments that reduce morbidity and mortality, and the authors propose that the LVEF threshold for HFrEF treatment be increased to ≤50%.

Wednesday 11th September 2019

Diabetes Screening: Laboratory vs Point-of-Care Glucose and Hemoglobin A1C Testing

An asymptomatic 57-year-old man with obesity, hypertension, and dyslipidemia requests screening for diabetes. Would you offer laboratory-based or point-of-care glucose or HbA1c testing?

Primary Care Provider Selection as an Essential Element of Value-Based Health Care

In the context of “attribution gaps” that leave payers uncertain which physicians are to be credited with patient care quality and outcome measures in accountable care organization (ACO) payment models, this Viewpoint discusses the importance of patient selection of primary care providers to patient-centered value-based care, and changes CMS will need to implement to integrate the measure.

Tuesday 10th September 2019

How Old Is Too Old to Be President?

This Medical News article reports on a recent analysis that concludes that older candidates’ ages shouldn’t be a concern in the 2020 presidential election.

Cardiovascular Corner: Prescription Omega-3s, Stroke Rehab, and Statins After Age 75

This Medical News article is an update on important clinical research in the world of heart disease and stroke.

Monday 9th September 2019

The 2019 Lasker Awards: Gavi the Vaccine Alliance and the Power of Vaccines

In this Viewpoint, the CEO of Lasker-Bloomberg Public Service Award winner Gavi, the Vaccine Alliance, describes its work improving access to affordable childhood vaccines in low-income countries.

The 2019 Lasker Awards: Discovery of T Cells and B Cells as the Basis of the Adaptive Immune System and Immunologic Function

In this Viewpoint, 2019 Albert Lasker Basic Medical Research Award winners Max Dale Cooper and Jacques F. A. P. Miller discuss their discovery of B and T cells, which provided the organizing principle of the adaptive immune system and launched the course of modern immunology.

The 2019 Lasker Awards: The Beginnings of Biomarker-Driven Drug Discovery in Cancer

In this Viewpoint, 2019 Lasker-DeBakey Clinical Medical Research Award winner H. Michael Shepard discusses development of trastuzumab, the first fully humanized monoclonal antibody for solid tumor treatment and the first tyrosine kinase inhibitor, for treatment of breast cancer.

Sunday 8th September 2019

The Relative Value Scale Update Committee—Time for an Update

This Viewpoint discusses how problems with the methodology, structure, and recommendations of the Relative Value Scale Update Committee can lead to outdated or inaccurate physician payment data and lower quality of care, and calls for the use of empirical data and patient-specific outcomes to inform physician reimbursement.

Thursday 5th September 2019

Candida auris Update, 2019-2020

This JAMA Insights Clinical Update reviews infection control and treatment strategies to manage Candida auris, a new drug-resistant fungal species that can cause severe invasive infection with high morbidity and mortality in patients with underlying comorbid illnesses.

Assessing Health Outcomes Attributable to Medicaid Expansion At 5 Years

This Viewpoint reviews evidence for associations between Medicaid expansion under the Affordable Care Act and self-reported health outcomes, condition-specific outcome measures from administrative data, and state and national health indicators for low-income populations.

Wednesday 4th September 2019

Joint Pain and Proteinuria

A 66-year-old man had bilateral carpal tunnel syndrome and 6 years of chronic joint pain and stiffness of the shoulders, hips, and knees. He reported occasional bruising around his eyes; physical examination showed raised soft tissue masses around the sternoclavicular joints and scapulae, and laboratory examination was notable for significant levels of protein and albumin. What is the diagnosis an...

What Is the Value of Market-Wide Health Care Price Transparency?

In the wake of a 2019 executive order requiring hospitals to publicly post paid prices and requiring clinicians, insurers, and health plans to provide estimated out-of-pocket costs to patients, this Viewpoint reviews available evidence about the likelihood that price transparency might influence consumer choice, put downward pressure on prices, and influence insurers to incentivize patients to see...

Tuesday 3rd September 2019

Clarification of Reporting of Potential Conflicts of Interest in 2 Articles

In the Viewpoint titled “Ten Steps the Federal Government Should Take Now to Reverse the Opioid Addiction Epidemic” published in the October 24/31, 2017, issue and in the Letter titled “Government Actions to Curb the Opioid Epidemic—Reply” published in the April 17, 2018, issue of JAMA, an author’s potential conflicts of interest disclosure statement was incomplete. In the Viewpoint, t...

Pigs Model Human Brains, Snake Fangs Inspire Microneedles, and Canines Advance Cardiac Imaging

This Medical News article discusses how pigs, rear-fanged snakes, and dogs may help improve our understanding of brain connectivity, vaccine delivery, and myocardial oxygenation.

Green Vegetables, Herbs, and Oils May Help Stabilize Patients Taking Warfarin

This Medical News article discusses recent research that shows increasing their vitamin K intake could help patients who take warfarin to maintain stable anticoagulation.

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