Latest Biotechnology, Pharmaceutical and Healthcare News from Nature Publishing

15:09 EST 23rd November 2017 | BioPortfolio

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Showing News Articles 1–25 of 7,800+ from Nature Publishing

Thursday 23rd November 2017

Neuromodulation: On the alert

Lineage divergence of activity-driven transcription and evolution of cognitive ability

Ability of sit-to-stand with hands reflects neurological and functional impairments in ambulatory individuals with spinal cord injury

Rheumatoid arthritis: Tocilizumab prevents progression of bone erosions

Osteoporosis: Teriparatide preferable for fracture prevention

Systemic lupus erythematosus: Effects of disease activity on pregnancy outcomes

Crystal arthritis: Stepping up febuxostat to treat gout flares

Neuroscience starts talking

Hydrogen-bearing iron peroxide and the origin of ultralow-velocity zones

Ultralow-velocity zones (ULVZs) at Earth’s core–mantle boundary region have important implications for the chemical composition and thermal structure of our planet, but their origin has long been debated. Hydrogen-bearing iron peroxide (FeO2Hx) in the pyrite-type crystal structure was recently found to be stable under the conditions of the lowermost mantle. Using high-pressure experiments and ...

Ligand-accelerated non-directed C–H functionalization of arenes

The directed activation of carbon–hydrogen bonds (C–H) is important in the development of synthetically useful reactions, owing to the proximity-induced reactivity and selectivity that is enabled by coordinating functional groups. Palladium-catalysed non-directed C–H activation could potentially enable further useful reactions, because it can reach more distant sites and be applied to substr...

Photonic quantum state transfer between a cold atomic gas and a crystal

Interfacing fundamentally different quantum systems is key to building future hybrid quantum networks. Such heterogeneous networks offer capabilities superior to those of their homogeneous counterparts, as they merge the individual advantages of disparate quantum nodes in a single network architecture. However, few investigations of optical hybrid interconnections have been carried out, owing to f...

Photonuclear reactions triggered by lightning discharge

Lightning and thunderclouds are natural particle accelerators. Avalanches of relativistic runaway electrons, which develop in electric fields within thunderclouds, emit bremsstrahlung γ-rays. These γ-rays have been detected by ground-based observatories, by airborne detectors and as terrestrial γ-ray flashes from space. The energy of the γ-rays is sufficiently high that they can trigger atmosp...

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

The spontaneous deamination of cytosine is a major source of transitions from C•G to T•A base pairs, which account for half of known pathogenic point mutations in humans. The ability to efficiently convert targeted A•T base pairs to G•C could therefore advance the study and

Lorenzo-Redondo et al. reply

REPLYING TOD. I. S.Rosenbloom, A. L.Hill, S. B.Laskey & R. F.SilicianoNature551, 10.1038/nature24634 (2017)In the accompanying Comment, Rosenbloom et al. present a model simulation that questions our report

Re-evaluating evolution in the HIV reservoir

ARISING FROMR.Lorenzo-Redondoet al. Nature530, 51–56 (2016); doi:10.1038/nature16933Despite antiretroviral therapy (ART), a latent reservoir of replication-competent HIV-1 persists in resting memory CD4+ T cells and precludes a cure. Lorenzo-Redondo et


Identity crisis.

Childhood obesity: A growing concern

Rising obesity means that more children are developing non-alcoholic fatty liver disease.

Disease progression: Divergent paths

Not everyone with a fatty liver goes on to develop more advanced disease. Understanding what triggers the progression could lead to better treatments.

Diagnostics: Missing the point

Conventional detection of advanced fatty liver disease relies on biopsy. Less onerous methods may help to save lives.

Drug development: Sprint finish

Biotechnology start-ups and pharmaceutical giants alike are charging ahead to develop therapies for the most serious form of non-alcoholic fatty liver disease

Fatty liver disease

Trailblazer: When Marie Curie went to Brazil

PhD jobs: Explore posts abroad

​​​​​​​PhD jobs: Support beyond academia

​​​​​​​PhD jobs: Revamp funding structures

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