Latest Biotechnology, Pharmaceutical and Healthcare News from Drug Discovery Development

06:07 EDT 20th March 2018 | BioPortfolio

Here are the most relevant search results for "Drug Discovery Development" found in our extensive news archives from over 250 global news sources.

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Showing News Articles 1–25 of 837 from Drug Discovery Development

Monday 19th March 2018

Expanded Indication for SPIRIVA Respimat for Patients 6 Years and Older

NewsBoehringer Ingelheim announced that an expanded indication for SPIRIVA Respimat (tiotropium Respimat) as add-on maintenance bronchodilator treatment in patients aged 6 years and older with severe asthma who experienced one or more severe asthma exacerbations in the past year, has been accepted by the regulatory authorities in the EU.

Trump Opioid Plan Includes Death Penalty for Traffickers

News President Donald Trump’s plan to combat opioid drug addiction nationwide calls for stiffer penalties for drug traffickers, including the death penalty where appropriate under current law, a top administration official said.

Dimethandrolone Undecanoate Shows Promise as Male Birth Control Pill

NewsA new birth control pill for men appears to be safe when used daily for a month, with hormone responses consistent with effective contraception, study researchers say.

Friday 16th March 2018

House to Try Again on Bill Easing Use of Unapproved Drugs

NewsThe House plans to try anew next week to approve a Republican bill making it simpler for fatally ill people to try unproven treatments. And this time, the measure seems certain to pass.

Restricting Blood Vessels Can Cut Liver Metastasis by 80 Percent

NewsResearchers achieved an 80% reduction in liver metastasis brought about by colon cancer. Nanoparticles were used to slow down the growth of the blood vessels that reach the tumor cells.

Thursday 15th March 2018

Alzheimer's Drug Trials Keep Failing- It May Be Because We Don't Understand the Disease

NewsA statistical analysis of the first three years of the study showed there was no chance the drug would work. The test was costing hundreds of millions of dollars with no hope it would ever help patients or come to market. Another promising anti-Alzheimer’s drug had failed.

Native American Overdose Deaths Surge Since Opioid Epidemic

NewsOverdose deaths in Native American communities have skyrocketed in the time the opioid epidemic has swept the U.S. and federal officials are looking for solutions.

FDA Breakthrough Therapy Designation for Erdafitinib in the Treatment of Metastatic Urothelial Cancer

NewsErdafitinib, an oral pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, shows promise as the first targeted agent for patients with metastatic urothelial cancer, one of the most common cancers.

BI, Vanderbilt University Expand Partnership to Develop Novel Treatment Approaches for Cancer

NewsBoehringer Ingelheim and Vanderbilt University announced the expansion of their successful existing collaboration to develop novel anti-cancer compounds.

Wednesday 14th March 2018

Sanofi, Regeneron to Make Praluent More Affordable for Patients with the Greatest Health Risk and Unmet Need​

NewsA precision medicine approach will focus efforts on high-risk patients, such as those who have had heart attacks or unstable angina and cannot reduce their LDL-C below 100 mg/dL despite maximally-tolerated statins.

Positive Topline Results from Second Phase 3 Study Evaluating Investigational Elagolix in Women with Uterine Fibroids

NewsAbbVie, in cooperation with Neurocrine Biosciences, Inc., announced that the Phase 3 ELARIS UF-II study (M12-817) of elagolix met its primary endpoint.

Preclinical Characterization of Therapeutic Antibodies Targeted at the Carboxy-terminus of Sonic Hedgehog

NewsEven though the Shh pathway is mainly quiescent in adults, the safety of Shh-targeting with therapeutic antibodies was questioned initially because not only does the N-terminus of the Shh protein play an important role in embryonic development, but Shh also plays a poorly understood role in tissue homeostasis and repair in adults.

NIR Chemical Imaging Can Help Maintain the Safety of Pharmaceutical Tablets

NewsIn a paper published in the Open Access, peer-reviewed journal Journal of Spectral Imaging, the authors report on the use of NIR chemical imaging for in-line feed frame monitoring.

Canakinumab Doesn’t Prevent Prediabetes from Progressing to Diabetes

NewsThe anti-inflammatory drug canakinumab had no effect on rates of newly diagnosed diabetes in people who had prediabetes (elevated blood sugar levels at risk of developing into diabetes).

Tuesday 13th March 2018

Blood Thinner Significantly Reduces Risk of Death After Non-cardiac Surgery

NewsResearchers have discovered that a blood-thinning drug, dabigatran, significantly reduces the risk of death, heart attack, stroke, and other heart or blood-vessel complications in patients who have a heart injury following major, non-cardiac surgery.

FDA Grants Priority Review to Merck’s Supplemental Biologics License Application for KEYTRUDA (pembrolizumab) for Treatment of Advanced Cervical Cancer

NewsMerck announced that the U.S. Food and Drug Administration (FDA) has accepted a new supplemental Biologics License Application (sBLA) and granted Priority Review for KEYTRUDA (pembrolizumab), the company’s anti-PD-1 therapy.

Monday 12th March 2018

Trial for Gout Drug Meets Primary Endpoint, Raises Safety Concerns

NewsFebuxostat, a gout drug that has been in use for nearly a decade, was found to significantly increase the risk of death, even though it did not raise the risk of the trial’s primary endpoint, a combined rate of fatal and nonfatal adverse cardiovascular events.

Trump Promising Consumers Digital-age Health Care Approach

NewsA smartphone app that lets Medicare patients access their claims information. Giving consumers a share of drug company rebates for their prescriptions. Wider access to websites that reliably compare cost and quality of medical tests.

INVOKANA (canagliflozin) Reduces Risk of Heart Failure-related Outcomes in Type 2 Diabetes Patients

NewsThe Janssen Pharmaceutical Companies of Johnson & Johnson announced results of a new analysis showing that INVOKANA (canagliflozin) significantly reduced the risk of cardiovascular (CV) death or hospitalization for heart failure (HHF) in patients with type 2 diabetes (T2D) at high CV risk.

Study Confirms CV Benefits for Type 2 Diabetes Patients Using SGLT-2 Inhibitors

NewsA real-world evidence study of more than 400,000 patients with type-2 diabetes, 74% of whom did not have a history of established cardiovascular disease, supports the association of CV benefits with use of Farxiga.

Friday 9th March 2018

Researchers Close to Understanding 'Disease Mechanisms' of ALS

NewsResearchers have been working with ubiquitin, a tiny molecule that tags obsolete proteins in a cell. They recently found that ubiquitin eliminates droplets of Ubiquilin-2 (UBQLN2) in solution.

Positive EU Approval for Labeling Update to GSK's Relvar Ellipta

NewsGlaxoSmithKline and Innoviva announced that the European Commission has approved a label update for the use of once-daily Relvar Ellipta (fluticasone furoate/vilanterol, FF/VI), an inhaled corticosteroid/long-acting β2-agonist combination, in patients whose asthma is already adequately controlled on both an inhaled corticosteroid and long-acting β2-agonist.

New Analyses Show Payer Utilization Management Criteria Deny Access to PCSK9 Inhibitors

NewsAmgen announced data from two new studies exploring barriers to access for PCSK9 inhibitors and the potential consequences of denying coverage for high-risk patients.

Thursday 8th March 2018

Herbalist Charged in Death of Diabetic Boy Treated with Oils

NewsAn herbalist who touted natural cures that helped him overcome cancer has been charged in the death of a 13-year-old diabetic boy who prosecutors said he treated with herbal oils instead of insulin.

FDA Approves HIV Treatment for Patients who Have Limited Treatment Options

NewsThe FDA approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past and whose HIV infections cannot be successfully treated with other currently available therapies.

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