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Latest Biotechnology, Pharmaceutical and Healthcare News from Bitesize Bio

06:35 EDT 17th July 2019 | BioPortfolio

Here are the most relevant search results for "Bitesize Bio" found in our extensive news archives from over 250 global news sources.

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Showing News Articles 1–25 of 60 from Bitesize Bio

Wednesday 17th July 2019

How History Shaped Modern Optical Microscopes, Part One: Simple and Compound Microscopes

Having some knowledge of microscope history can be beneficial to understanding and appreciating specific configurations and components, and how they produce an optimal image. For example, practically all laboratory microscopes use achromatic objectives to partly compensate for chromatic aberration. For high-quality imaging, fluorescence microscopy, and photomicroscopy, fluorite and apochromatic ob...

Tuesday 16th July 2019

An Introduction to Digital Images in Publications

Previously, I wrote about the different ways to use scientific illustration to communicate research. In this article, I will introduce the technical aspects of digital images and the most common image file types that scientists will encounter when preparing images for publication. Raster Versus Vector Digital images are classified based on how information is stored.… The post An Introduction...

Tuesday 9th July 2019

Struggles of a Life Scientist

Working late nights or weekends in the lab—we’ve all been there. Why isn’t your cell culture considerate enough to get to exponential phase during normal business hours, anyway? Maybe you just need utter peace and quiet while you pipette hundreds of wells worth of stinky beta-mercaptoethanol. Or perhaps you’re using your wealth of microbiology knowledge… The post Struggles of a Life ...

Monday 8th July 2019

Reducing GC Bias in WGS: Moving Beyond PCR

WGS technologies have seen significant progress since the completion of the Human Genome Project in 2003. First-generation Sanger Sequencers were limited by lengthy run times, high expenses, and throughputs that read only tens of kilobases per run. The arrival of second-generation sequencers in the mid-2000s brought about the plummeting of sequencing costs and run times,… The post Reducing G...

How to Improve Your WGS DNA Library

In whole genome sequencing (WGS) initiatives it is not enough to simply sequence the whole length of the genomic DNA sample just once. This is because genomes are usually very large. The human genome, for example, contains approximately 3 billion base pairs. Although sequencing accuracy for individual bases is very high, when you consider large… The post How to Improve Your WGS DNA Library a...

Wednesday 19th June 2019

How to Get a Scientific Research Job in the US (If You Are Coming from Elsewhere)

Growing up in Australia, I remember a common phrase: ‘only in America’. Sometimes this was in reference to bizarre cultural events or phenomena but it was generally accepted that the USA was an extraordinary place, where everything was bigger, brighter, and more outrageous. America has fostered a culture of big ideas and innovation, partly because… The post How to Get a Scientific Resear...

Friday 14th June 2019

NGS Target Enrichment Strategies

Next-generation sequencing (NGS) has ushered in a new era of understanding of both the inner workings and the function of the genome. NGS allows researchers to look at traits—including diseases—that are linked to differences or mutations in an individual’s genes. Since only about 1% of the human genome constitutes genes that code for proteins, several… The post NGS Target Enrichment St...

Wednesday 29th May 2019

What to Expect When Working with a Scientific Recruiter

Have you ever wondered what it would be like if someone helped you step-by-step through your job search? A good recruiter does exactly that! Recruiters provide value to job-seekers by reviewing resumes, finding jobs that may be a good fit, and providing interview tips. But how does that process work? In this article we’ll cover… The post What to Expect When Working with a Scientific Recrui...

What to Expect When Working with a Recruiter

Have you ever wondered what it would be like if someone helped you step-by-step through your job search? A good recruiter does exactly that! Recruiters provide value to job-seekers by reviewing resumes, finding jobs that may be a good fit, and providing interview tips. But how does that process work? In this article we’ll cover… The post What to Expect When Working with a Recruiter appeare...

Tuesday 28th May 2019

7 Types of  Software Apps You NEED in Your (Science) Life

Technology has advanced to the point that most of us check our phones the first thing every morning. Software apps allow us to have technology at our fingertips throughout our daily lives. But, what about our science lives? Yes, apps are just as useful for our science lives! Here are 10 that caught my eye.… The post 7 Types of  Software Apps You NEED in Your (Science) Life appeared first on...

Wednesday 22nd May 2019

How to Marie Kondo Your Laboratory

Does your laboratory resemble the nest of an overly enthusiastic laboratory rat that went on a scavenger hunt and squirrelled away all that it has found? Do you find yourself playing Jenga with stacks of Petri dishes and freezer boxes? Have you ever attempted to decipher the meaning of the mysterious string of numbers on… The post How to Marie Kondo Your Laboratory appeared first on Bitesize...

Tuesday 30th April 2019

How to Feed Fruit Fly Larvae Small Molecules

Generally speaking, fruit flies are a great model system. Not only are they small, thus taking up very little space in the lab, but their adult lifespan is only 40-60 days, so you can track age-dependent changes without having to wait months and months. Fruit flies also display complex behaviors and more than 75% of… The post How to Feed Fruit Fly Larvae Small Molecules appeared first on Bit...

Tuesday 23rd April 2019

Cryofixation and Chemical Fixation for Electron Microscopy

Specimen preparation is the most important aspect of biological electron microscopy (EM), as it influences everything from the preservation of the sample itself to the kind of information that can be obtained. It is vital to define the questions you are asking of the sample before embarking on an electron microscopy project. This enables you… The post Cryofixation and Chemical Fixation for E...

Wednesday 17th April 2019

The EMSA – Teaching an Old Dog New Tricks

Probing Nucleic Acid-Protein Interactions with EMSA The electrophoretic mobility shift assay (EMSA) is a powerful technique for detecting specific-binding of nucleic acid-protein complexes. Over the past 30 years, EMSA has been the “go to assay” to investigate the qualitative interactions between nucleic acids (DNA or RNA) and nucleic-acid binding proteins. Through the use of radio-labeledR...

Tuesday 16th April 2019

Mastering the Art of Isolating Pure Alveolar Epithelial Cells

Alveolar epithelial cells (AECs) are one of the major types of lung cells that can be used to analyze the response of lung epithelia to external agents. AECs from mouse lungs can thus be utilized as an in vitro model of diseases. AECs are indispensable for studying lung development, injury, and repair. People working on… The post Mastering the Art of Isolating Pure Alveolar Epithelial Cells ...

Thursday 11th April 2019

Emerging Model Microorganisms Take to the Stage

Estimates indicate that there may be up to 2 billion living species of organisms, each with conserved and unique biological mechanisms that are vital for survival. How do scientists understand them all? Enter model organisms. Model organisms, as the name implies, are living things which are used as representative models for understanding other organisms. They… The post Emerging Model Microor...

Monday 8th April 2019

Isolating Bacterial RNA from Blood

For many decades, the only way to detect sepsis – bacterial growth in blood – was isolating the bacteria and growing bacterial colonies on a special medium. This was done by first spinning down the blood, which brought the blood cells and bacteria into the pellet. The pellet was spread on a blood agar plate… The post Isolating Bacterial RNA from Blood appeared first on Bitesize B...

Thursday 4th April 2019

Ultramicrotomy for Electron Microscopy

Ultramicrotomy is the process by which a sample is cut into very thin slices or “sections”, usually for imaging by transmission electron microscopy (TEM) or relatively new techniques using scanning electron microscopy (See Array tomography in three dimensional scanning electron microscopy for biology). This technique requires a bit of finesse, and this article will help… The post Ultrami...

Wednesday 3rd April 2019

Microscope Finder Slides: Their History, Development, and Use

Have you ever been looking through a box of slides and found something that you want to image or look at later, or even show to one of your colleagues or supervisor? Finding that exact spot on the slide at a later date can prove to be difficult- using a marker pen on the coverslip… The post Microscope Finder Slides: Their History, Development, and Use appeared first on Bitesize Bio.

Wednesday 27th March 2019

How (and Why) to Label Nucleic Acids

Have you ever wished you could snag individual strands of DNA or RNA with a lasso? Or look at them one by one, figuring out exactly where they are or what they are doing? Fortunately, there are techniques that exist to label nucleic acids for their visualization and purification! Nucleic acids can be labeled at… The post How (and Why) to Label Nucleic Acids appeared first on Bitesize Bio.

Tuesday 26th March 2019

Gender Reveal: How to Determine the Gender of Drosophila Larvae

Drosophila melanogaster, otherwise known as the common fruit fly, is one of the oldest and most powerful model systems used in biology. Fruit flies are cheap to maintain, and have a shorter life cycle and higher fecundity than mammalian models. They also have extraordinary genetic tools with which to investigate many molecular and cellular questions.… The post Gender Reveal: How to Determine...

Monday 11th March 2019

The Beginner’s Guide to Reading Plasmid Maps

Very often plasmid maps, especially historical ones that are hand-drawn by a long-forgotten PhD student, are a puzzle. What are these arrows and boxes? Where do I start? Don’t worry, we have a crash course introduction into deciphering plasmid maps. Familiarizing Yourself with Your Plasmid of Interest Let’s start with a classic plasmid: pBR3221. It… The post The Beginner’s Guide to Rea...

Thursday 7th March 2019

Greenhouse Maintenance: Keeping Your (Green) Laboratory Clean

Cleaning the lab is one of the hardest jobs because it’s dull and repetitive. However, nobody in their sound scientific mind would argue that this can be avoided. Dust accumulates bugs, bacteriophages, and RNAses that can stray into your experiment and ruin it. Old boxes piling up is a fire hazard. Anybody who refuses to… The post Greenhouse Maintenance: Keeping Your (Green) Laboratory Cle...

Wednesday 6th March 2019

An Introduction to Alexa Dyes

Long before “Alexa” was a household name, Alexa dyes were an established series of fluorescent dyes. The inventor Richard Paul Haugland named the dyes after his son Alex. Originally a trademark of Molecular Probes, the Alexa family is now a part of Thermo Fisher Scientific. Alexa dyes are frequently used as labels in fluorescence microscopy,… The post An Introduction to Alexa Dyes appear...

Thursday 28th February 2019

10 Tips on Mating Mice Successfully

Tiny, furry, spinning around a wheel – few creatures are as endearing as the lab mouse. Trying to obtain reproductive success with them, however, can leave you spinning your own wheels. Why is it that what works so well for the animal facility staff, or experienced technician, seems to be beyond your reach? After all,… The post 10 Tips on Mating Mice Successfully appeared first on Bite...


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