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Latest Biotechnology, Pharmaceutical and Healthcare News from Healio

17:34 EDT 19th July 2018 | BioPortfolio

Here are the most relevant search results for "Healio" found in our extensive news archives from over 250 global news sources.

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Showing News Articles 1–25 of 1,400+ from Healio

Thursday 3rd May 2018

Estrogen plus spironolactone therapy not associated with prolactin levels in transgender women

Joshua D. SaferTransgender women on a long-term regimen of estrogen and spironolactone therapy did not experience a clinically relevant change in prolactin level, suggesting the therapy combination is safe in this population, according to findings from a retrospective study published in Endocrine Practice.The data suggest that it may be unnecessary to monitor prolactin in patients receiving estrog...

Novel method enhances accuracy of LDL estimates

LAS VEGAS — A novel method using non-HDL and triglyceride values estimated LDL better than the Friedewald method in patients who reduced their LDL with PCSK9 inhibition, according to data presented at the National Lipid Association Scientific Sessions.Seth S. Martin, MD, MHS, assistant professor of medicine and co-director of the Advanced Lipid Disorders Center at the Johns Hopkins Ciccarone Cen...

Reproductive factors influence diabetes risk in women

Girls who enter menarche at age 10 years or younger are 18% more likely to develop type 2 diabetes vs. girls who enter menarche at age 13 years or older, whereas women who have never given birth are at greater risk for the disease vs. women who have had at least two children, according to an analysis of pooled data published in Diabetes, Obesity and Metabolism.“Although the ongoing epidemic of o...

Wednesday 2nd May 2018

FDA declines proposed Rituxan biosimilar from Sandoz

The FDA has rejected approval of Sandoz’s biologics license application for GP2013, a proposed rituximab biosimilar, issuing a Complete Response Letter for the product.“While disappointed, Sandoz remains committed to further discussions with the FDA in order to bring this important medicine to U.S. patients as soon as possible,” Sandoz said in a statement. “There is a substantial unmet nee...

At-home OCT monitoring of retinal disease a possibility

HONOLULU — A home-care OCT monitoring device could reduce the cost and burden of treatment for patients with retinal disease, according to a researcher here.Claus von der Burchard, MD, and colleagues have developed an off-axis full-field time-domain OCT technology intended for patient use at home to monitor their retinal disease.“What [age-related macular degeneration and diabetic eye disease]...

VIDEO: Erythrocyte velocity technique could have implications in glaucoma, DR

HONOLULU — Osamah Saeedi, MD, discusses his research regarding the velocity of ocular erythrocytes at the Association for Research in Vision and Ophthalmology meeting here. The new technique involves labeling red blood cells with fluorescent dye to measure their speed, which could help understand diseases such as glaucoma and diabetic retinopathy, he said.

Quarterly anti-VEGF dosing for AMD improves vision in some patients

HONOLULU — A subset of patients receiving anti-VEGF treatment for neovascular age-related macular degeneration respond to treatment with less-than-monthly dosing, according to a poster presented here at the Association for Research in Vision and Ophthalmology meeting.David A. Eichenbaum, MD, and colleagues compiled data from a group of studies that looked at dosing frequency of Lucentis (ranibiz...

Avedro lands $25 million financing round

Avedro announced in a press release it has received a commitment of $25 million in financing led by Lilly Asia Ventures, with participation from existing investors OrbiMed Advisors, InterWest Partners and HealthQuest Capital.“This new funding brings together an exceptional syndicate of investors who are committed to helping us achieve [our] goal,” Reza Zadno, PhD, CEO of Avedro, said in the re...

Autoimmune thyroiditis linked to depression, anxiety disorders

Patients with autoimmune thyroiditis had higher depression and anxiety disorder scores than healthy patients, according to findings published in JAMA Psychiatry.“Despite growing interest in the psychiatric implications of [autoimmune thyroiditis], most published studies still focus on its somatic effects,” Eva-Maria Siegmann, BSc, department of psychiatry and psychotherapy, Friedrich-Alexander...

VIDEO: SD-OCT provides biomarkers for predicting DME treatment

HONOLULU — At the Association for Research in Vision and Ophthalmology meeting here, Dinah Zur, MD, discusses how spectral-domain OCT can help individualize treatment of diabetic macular edema by providing predictive biomarkers.

Program broadens pre-approval access to volanesorsen

Akcea Therapeutics announced its global early access program for volanesorsen, an investigational drug for treatment of patients with familial chylomicronemia syndrome, has been expanded.Volanesorsen, which is in development for treatment of the rare lipid disorder familial chylomicronemia syndrome (FCS) by reducing the production of apolipoprotein C-III, is under regulatory review in the U.S, Eur...

OCTANe partners with CEDARS/ASPENS for OTS 2018

OCTANe has partnered with the CEDARS/ASPENS Society for its annual Ophthalmology Technology Summit, which will be held Friday, June 29, at the Fashion Island Hotel in Newport Beach, California.The meeting will bring together leading ophthalmology technologists, researchers, clinicians and entrepreneurs for a 1-day forum to showcase innovations and foster partnerships. Events at OTS 2018 will focus...

Many unknowns surround medical marijuana

NEW ORLEANS — Though physicians in more than two dozen states, Washington, D.C., Puerto Rico and Guam have laws that allow medical marijuana’s use, there is still a lot of uncertainty over its medicinal value, according to a speaker at the ACP Internal Medicine Annual Meeting.“There are very little scientific data to support the approximately 50 indications where medical marijuana could be u...

VIDEO: Capillary perfusion deviation mapping can detect early diabetic retinopathy

HONOLULU — Single-scan capillary perfusion deviation mapping using OCT imaging can assist in identifying and scaling early diabetic retinopathy, according to Richard Rosen, MD, who presented a paper on the subject at the Association for Research in Vision and Ophthalmology meeting here.

Coffee drinking linked to hip fracture risk in postmenopausal Chinese women

Drinking at least four cups of coffee per day may confer a greater risk for hip fracture in postmenopausal Chinese women, whereas moderate coffee consumption appears to reduce risk, according to results published in Bone.Researchers found no associations between fracture risk and tea consumption.Zhaoli Dai, PhD, a postdoctoral fellow at Boston University School of Medicine, and colleagues evaluate...

In metabolically healthy obesity, no link between proinflammatory diet, all-cause mortality

Among adults with metabolically healthy obesity, a proinflammatory diet is not associated with increased risk for all-cause and cardiovascular mortality, but this risk persists for those with metabolically unhealthy obesity who adhere to the same diet, according to findings published in Clinical Nutrition.Yong-Moon Mark Park, MD, PhD, MS, an epidemiologist with the National Institute of Environmen...

Lymphoma rates in Xeljanz clinical trials for RA stable

In a review of clinical trials of tofacitinib, lymphoma rates among patients with rheumatoid arthritis who received the drug were stable over time, with minimal differences in the baseline characteristics of those with and without lymphoma, according to findings published in Arthritis Care and Research.“Safety events of special interest related to JAK involvement in immune function, including ly...

Tuesday 1st May 2018

Rho kinase inhibitor added to glaucoma treatment options

HONOLULU — Once daily netarsudil is an “excellent addition” to glaucoma treatments, Janet B. Serle, MD, said at the Association for Research in Vision and Ophthalmology meeting here. The treatment is now available in the U.S.The rho kinase inhibitor netarsudil 0.02% (Rhopressa, Aerie Pharmaceuticals) lowers IOP and is well tolerated, she told Healio.com/OSN, explaining a poster presentation ...

Topical treatment for DME tolerated in first-in-human trial

HONOLULU — Safety and tolerability objectives were met in a phase 1/2 first-in-human study of topical SF0166, a topical ophthalmic solution candidate for treatment of diabetic macular edema, a speaker said here.“Safety and tolerability were excellent, and there was no evidence of corneal toxicity,” D. Scott Edwards, PhD, said at the Association for Research in Vision and Ophthalmology meetin...

'Replacing prednisone' remains top priority for emerging vasculitis therapies

Paul MonachBOSTON — Avacopan, an oral C5aR inhibitor currently being studied as an investigational treatment for granulomatosis with polyangiitis and microscopic polyangiitis, may be the first drug developed specifically to treat vasculitis, according to Paul Monach, MD, PhD, chief of the rheumatology section for the VA Boston Healthcare System.“Mine is one of many sites involved in a very enc...

VIDEO: OCTA can lead to better understanding of diabetic retinopathy

HONOLULU — At the Association for Research in Vision and Ophthalmology meeting here, Javier Zarranz-Ventura, MD, PhD, FEBO, discusses a large-scale prospective study evaluating the use of OCT angiography in assessing diabetic retinopathy progression.

Targeted laser photocoagulation treats select cases of diabetic retinopathy

HONOLULU — Targeted retinal photocoagulation may be used to treat severe nonproliferative diabetic retinopathy as well as some cases of proliferative diabetic retinopathy, according to a poster presented here.Pallavi Singh, MD, of Dr. Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, and colleagues undertook a nonrandomized, prospective, interventional study of 30 treatment-naive eyes w...

VIDEO: Dexamethasone inserts show success in eyes with DME

HONOLULU — Repeated dexamethasone inserts are a safe option for diabetic macular edema, especially for treatment-naive eyes, according to an International Retina Group study presented by Catharina Busch, MD, at the Association for Research in Vision and Ophthalmology meeting here.

Inclisiran reduces LDL in variety of populations

LAS VEGAS — Inclisiran, an RNA interference therapeutic targeting PCSK9, safely reduced LDL in various patient populations and subgroups, according to a late-breaking clinical trial presented at the National Lipid Association Scientific Sessions.David Kallend, MBBS, chief medical officer of The Medicines Company, discussed analyses of the ORION trials.As Cardiology Today previously reported, the...

VIDEO: Study finds NovaTears can increase tear film thickness

HONOLULU — At the Association for Research in Vision and Ophthalmology meeting here, Gerhard Garhöfer, MD, discusses a study investigating the effect of NovaTears (Novaliq) on tear film thickness in dry eye patients.


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