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Latest "Cytochrome P450 11B2 Mitochondrial Aldosterone Synthase Cytochrome P450Aldo" News Stories

22:19 EDT 26th March 2019 | BioPortfolio

Here are the most relevant search results for "Cytochrome P450 11B2 Mitochondrial Aldosterone Synthase Cytochrome P450Aldo" found in our extensive news archives from over 250 global news sources.

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Showing "Cytochrome P450 11B2 Mitochondrial Aldosterone Synthase Cytochrome P450Aldo" News Articles 1–25 of 351

Monday 25th March 2019

Sleep and Aging Share Connection with Oxidative Stress

After drinking a mysterious potion, Rip Van Winkle slept for 20 years and finally awoke an old man. Perhaps he would have avoided the potion had it been labeled “oxidative stress,” which refers to byproducts of mitochondrial activity that have been associated with lifespan, aging, and degenerative disease. Oxidative stress, scientists now report, influences sleep-control […] The post Sle...


Sunday 24th March 2019

Biologists have identified 'doppelganger' frogs with different genes

(Ural Federal University) Biologists have found that lake frogs of the same 'appearance' have different mitochondrial DNA. Such heterogeneous genetics probably helps to better adapt to the environmental conditions.

Friday 22nd March 2019

A novel TUFM homozygous variant in a child with mitochondrial cardiomyopathy expands the phenotype of combined oxidative phosphorylation deficiency 4


Thursday 21st March 2019

Obese mouse mothers trigger heart problems in offspring

(Washington University School of Medicine) Mitochondria manufacture energy in every cell of the body, including heart muscle cells. A new study from Washington University School of Medicine in St. Louis shows that cardiac mitochondria are abnormal in the offspring of mouse mothers that become obese due to a high-fat, high sugar diet. Those offspring then pass on the mitochondrial defects at least ...

Poxel Reports Financial Results for Full Year 2018 and Provides Corporate Update

Executed strategic agreement for Imeglimin with Roivant Sciences; potential for up to USD 600 million in regulatory and development milestone payments and sales-based payments plus royalties on net sales Roivant concurrently invested USD 15 million (approximately EUR 12 million) in Poxel through subscription in newly-issued ordinary ...

A potassium channel β-subunit couples mitochondrial electron transport to sleep

Mitochondrial localization of PABPN1 in oculopharyngeal muscular dystrophy

Wednesday 20th March 2019

Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression

Proteintech Announces Travel Grant Winners for AACR Annual Meeting 2019

Proteintech, the benchmark in antibodies, today announced the winners of the 2019 American Association for Cancer Research (AACR) Annual Meeting Travel Grant awards. Uday Pratap of University of Texas Health Science Center at San Antonio and Renzo Perales-Linares of the University of Pennsylvania have each been awarded $1,000 each to cover expenses to atte...

Androgen receptor in prostate cells found to regulate mitochondrial processes

Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment is known as androgen...

Tuesday 19th March 2019

LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation

NeuroPointDX to Present Precision Medicine Approaches to Diagnosing and Treating Autism at National TACA Autism Conference

Company Will Present New Data from the 1,100 Patient Clinical Study, the Children’s Autism Metabolome Project (CAMP) NeuroPointDX, a business unit of Stemina Biomarker Discovery, today announced the company will present recent data from the Children’s Autism Metabolome Project (CAMP ), its large, comprehensive clinical study, supp...

Monday 18th March 2019

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme

Androgen receptor, treatment target for prostate cancer, imports into mitochondria

(University of Alabama at Birmingham) Androgens stimulate prostate cancer cells to grow. Many drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor, or AR. Researchers have discovered a new function of the AR in prostate cells -- the AR is imported into and localizes to mitochondria of the cell, where it plays a novel role in regulating multiple mito...

Poxel Announces Participation at the Oppenheimer 29th Annual Healthcare Conference

POXEL S.A. (Euronext – POXEL - FR0012432516), a biopharmaceutical company focused on the development of innovative treatments for metabolic disorders, including type 2 diabetes and non-alcoholic steatohepatitis (NASH), announced today that it will be featured as a presenting company at the Oppenheimer 29th Annual Healthcare Conference.

Sunday 17th March 2019

Clear Solutions Licenses HA Synthase Technology from Mayo Foundation

Clear Solutions Biotech Inc. (Stony Brook, NY) has licensed the rights to use and develop applications related to hyaluronic acid (HA) synthase genes, enzymes, and associated technology from the Mayo Foundation for Medical Education and Research (Rochester, MN)...

Friday 15th March 2019

Multi-omics identify xanthine as a pro-survival metabolite for nematodes with mitochondrial dysfunction

Aberrant mitochondrial function contributes to the pathogenesis of various metabolic and chronic disorders. Inhibition of insulin/IGF-1 signaling (IIS) represents a promising avenue for the treatment of mitochondrial diseases, although many of the molecular mechanisms underlying this beneficial effect remain elusive. Using an unbiased multi-omics approach, we report here that IIS inhibition reduce...

GenSight Biologics Announces Presentation of 72-Week Data From the REVERSE Phase III Trial of GS010 at the 45th Annual Meeting of NANOS

Regulatory News: GenSight Biologics (Paris:SIGHT) (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma company focused on discovering and developing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, announced today that the 72-week results from the REVERSE Phase III clinical tria...

Study shows how cell death can be triggered by a mitochondrial enzyme

Cytochrome c is a small enzyme that plays an important role in the production of energy by mitochondria.

Thursday 14th March 2019

Stains on ‘Jack the Ripper’ Shawl Probed with Science

ArticleA controversial “shawl” ostensibly connected to the third victim of Jack the Ripper has turned up mitochondrial DNA.

Wednesday 13th March 2019

How a mitochondrial enzyme can trigger cell death

(University of Groningen) Cytochrome c is a small enzyme that plays an important role in the production of energy by mitochondria. It is also involved in signaling dangerous problems that warrant apoptosis, or programmed cell death. Using solid-state NMR, University of Groningen Associate Professor Patrick van der Wel and colleagues from the University of Pittsburgh have discovered that the signal...

Tuesday 12th March 2019

Gene behind mitochondrial disease has more varied effects than previously thought

For more than two decades, mutations in a gene located in the DNA of mitochondria have been classified as a mitochondrial disease and linked to a particular set of symptoms.

Santhera Completes Patient Enrollment in Phase IV Long-term Study with Raxone® for the Treatment of Leber's Hereditary Optic Neuropathy

Santhera Pharmaceuticals Holding AG / Santhera Completes Patient Enrollment in Phase IV Long-term Study with Raxone® for the Treatment of Leber's Hereditary Optic Neuropathy . Processed and transmitted by West Corporation. The issuer is solely responsible for the content of this announcement. Pratteln, Switzerland, March 12, 2019 - Santhera Pharmaceuticals (SIX: SANN) anno...

Monday 11th March 2019

AMPK-mediated activation of MCU stimulates mitochondrial Ca2+ entry to promote mitotic progression

Gene behind long-recognized mitochondrial disease has highly varied effects

(Children's Hospital of Philadelphia) Mutations in the mitochondrial gene mt-ATP6, which encodes an essential part of the mitochondrial motor known as ATP synthase that generates cellular energy, are much more variable than previously thought. This prompts the need to develop more precise clinical tests that can better determine the course of treatment for patients affected by mitochondrial disord...


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