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08:26 EST 22nd November 2019 | BioPortfolio

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Friday 22nd November 2019

Treading with Caution

Over the past year as the FDA has cracked down on laboratory developed tests and other pharmacogenetic tests that reference specific drugs or drug classes unless they have been approved agency. The FDA issued “Safety Communication” warned patients and healthcare providers not to change patient medication regimens based on results from genetic tests claiming to predict a patient’s response to...


VBI Vaccines Presents Early GBM Tumor Response and Immunologic Data from Part B of Ongoing Phase 1/2a Study of VBI-1901 at the 2019 SNO Annual Meeting  

33% reduction in tumor size observed in one patient in Part B – reduction sustained through two consecutive MRI scans 6-month overall survival (OS) now available for Part A demonstrated benefit for vaccine responders (100%) vs. non-responders (63%)   VBI Vaccines Inc. (Nasdaq: VBIV) (VBI), a commercial-stage biopharmaceutical company developing next-generation infectious disease and imm...

SHEPHERD Names Dr. Catharine Young Executive Director of the SHEPHERD Foundation

Young, former leadership at the Biden Cancer Initiative, brings to bear science policy expertise to improve rare cancer patients’ journey SHEPHERD and its founder David Hysong today announced it has named Catharine Young, Ph.D., as the Executive Director of the SHEPHERD Foundation. SHEPHERD was founded to fill the gaps facing the rare cancer system, and to place the focus back on the patient. ...


GE Healthcare and Sepsis Alliance Collaborate to Improve Treatment of Sepsis – Leading Cause of Death in U.S. Hospitals

GE Healthcare joins with Sepsis Alliance to present the Can We Help ‘Solve’ Sepsis, Together webinar series and sponsors the Sepsis Coordinator Network SAN DIEGO (PRWEB) November 22, 2019 Sepsis Alliance, the nation’s first and leading sepsis organization, and GE Healthcare, a leading provider of medical imaging, monitoring, biomanufacturing, and cell and gene therapy technologies, today an...

Zymeworks Highlights Advancing Clinical Collaboration with BeiGene and Updated ZW25 Phase 1 Data in HER2-Expressing Cancers at ESMO Asia Congress

Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional therapeutics, today announced updated Phase 1 data for single agent ZW25 in heavily pretreated patients with HER2‑expressing solid tumors in a mini oral presentation by Dr. Do-Youn Oh, study investigator and Professor at Seoul National University, at the ESMO Asia 2019 Congress, taking place Novem...

Study underscores the influence of sensory processing in multiple sclerosis

A team of researchers published new findings about the role of sensory processing and disease characteristics in the functional status of individuals with multiple sclerosis.

Thursday 21st November 2019

A Nature paper reports that distinct doughnut-shaped circles of extrachromosomal DNA (ecDNA) are found abundantly in human tumor cells and boost aggressiveness and resistance to therapies. https://go.nature.com/2Ox9xOf pic.twitter.com/5hgbYb5nFz

A Nature paper reports that distinct doughnut-shaped circles of extrachromosomal DNA (ecDNA) are found abundantly in human tumor cells and boost aggressiveness and resistance to therapies. https://go.nature.com/2Ox9xOf  pic.twitter.com/5hgbYb5nFz

Merck opens new office in Sydney's Macquarie Park

Science and technology company Merck has officially opened its new Sydney office in the innovation hub of Macquarie Park — a move that seeks to further the company’s local growth opportunities and brings together, for the first time in one location, more than 120 employees from Merck’s health care, life science and performance materials divisions, who were previously based across the Sydney ...

New study shows how cancer survivors develop opioid addictions

(Oxford University Press USA) Opioids play an important role in how cancer patients manage pain, but the ongoing opioid epidemic has raised concerns about their potential for abuse. A new study in the Journal of the National Cancer Institute reveals that several factors are associated with a risk for persistent opioid use, including younger age, white race, unemployment at the time of cancer diagn...

Molecule could be targeted to slow MS progression

By identifying a molecule that plays a role in multiple sclerosis, Canadian researchers have paved the way for new therapies to treat this autoimmune disease. Multiple sclerosis (MS) can cause symptoms such as extreme fatigue, lack of coordination, vision problems, cognitive impairment and mood changes. 60% of adults with MS are between the ages of 20 and 49 and women are three times more likely ...

5 Things to Know About Americans and Their Smart Speakers

(Pew Research) – Smart speakers such as Amazon Echo or Google Home have gained popularity over the last several years, and consumer experts found that these devices were especially popular with holiday season gift buyers last year. But even as … Read More

Combos Could Unlock Major Immunotherapy Benefits in Ovarian Cancer

John Hays, MD, PhD, discusses ongoing research with immunotherapy in ovarian cancer, challenges with determining predictive biomarkers of response, and promising emerging modalities.

Study of the antitumour effects and the modulation of immune response by histamine in breast cancer

Azitra Names Bertonis as Chief Operating Officer

Jeanne Bertonis has joined Azitra as COO. In this role, she will be responsible for building the clinical operations team as the company preps for multiple clinical trials in 2020, according to a statement from Azitra CEO Richard Andrews. Bertonis was previously CEO of Visgo Therapeutics – which she co-founded – and has held several […]

Former Shire Exec Robertson Joins Yumanity

Cambridge, MA-based Yumanity Therapeutics has named Brigitte Robertson to the role of chief medical officer. Most recently, she was the therapeutic area head of neuroscience global clinical development at Shire, which was then acquired by Takeda (NYSE: TAK). Robertson also held roles at Sunovion Pharmaceuticals in clinical development and experimental medicine, and GlaxoSmithKline (NYSE: GSK) [...

New genetic risk loci found for SSc

Exactech Expands Global Direct Operations with Acquisition of Italian Distributor

Exactech, a developer and producer of innovative implants, instrumentation and computer-assisted technologies for joint replacement surgery announced today the acquisition of its independent distribution partner, Exactech Italia S.p.A., creating a new corporate subsidiary, effective Nov. 21, 2019. The purchase included all shares of the Province of Brescia-based importer and distributor of Exac...

On National Rural Health Day, University of Maryland Extension Reports a High-Impact Year Related to Farm Stress Management Education

Program Reports Strong Engagement and Positive Takeaways from Robust Training Resources. COLLEGE PARK, Md. (PRWEB) November 21, 2019 In early 2018, national reports from USDA, private industry and farm organizations began talking about another “farm crisis.” USDA Economic Research Service forecasted a decrease in farm income that would be the lowest level in nominal terms since 2006. Weather,...

.@HowardYChang and colleagues show that following anti-PD-1 therapy in patients with basal or squamous cell carcinoma, the CD8+ T cell response largely consists of an expanded and exhausted repertoire of new, rather than pre-existing, T cell clones | htt

. @HowardYChang and colleagues show that following anti-PD-1 therapy in patients with basal or squamous cell carcinoma, the CD8+ T cell response largely consists of an expanded and exhausted repertoire of new, rather than pre-existing, T cell clones | http://go.nature.com/37qrxCK  | pic.twitter.com/1uzNvrKIzo

Ergotron Receives Two Nightingale Awards at Healthcare Design Expo

Ergotron was honored with two Nightingale Awards at the 2019 Healthcare Design Expo & Conference in New Orleans, Louisiana. The WorkFit® Elevate™ Sit-Stand Wall Desk received a silver award in the category of clinician support furniture, and the CareFit™ Enclosure Wall-Mount Computer Workstation won a gold award in the category of clinical architectural products. This press release featu...

Madrona Awards 2019 Madrona Prize to UW Project That Applies Artificial Intelligence to Build Accurate and Easy-to-Use Models for Physicians to Employ in Time-Sensitive and Potentially Life-Saving Situations

Madrona Venture Group awarded the 14th Annual Madrona Prize last night to the CoAI team at the University of Washington’s Paul G. Allen School of Computer Science & Engineering. CoAI: Cost Aware Artificial Intelligence for Health Care applies ML to help

The intragraft vascularized bone marrow component plays a critical role in tolerance induction after reconstructive transplantation

Response to: Olry de Labry Lima A et al., Cost-effectiveness of lenalidomide maintenance in patients with multiple myeloma who have undergone autologous transplant hematopoietic progenitor cells

MedSpeed Elevates Role of Technology in Transportation With New Chief Information Officer Role

MedSpeed has promoted Jim Van Duyn to the newly created chief information officer (CIO) role. He will work closely with other members of the executive and management teams to integrate new technology into internal and customer-facing processes. ELMHURST, Ill. (PRWEB) November 21, 2019 MedSpeed, the U.S. market-leading provider of healthcare intra-company logistics, has promoted Jim Van Duyn to th...

Final OTC Sunscreen Monograph Postponed, FDA Leadership Confirms

The US FDA is still working through more than 20,000 comments on its February proposed rule to establish a final...   


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