Latest "Cell Signaling Technologies" News Stories

16:19 EDT 25th April 2018 | BioPortfolio

Here are the most relevant search results for "Cell Signaling Technologies" found in our extensive news archives from over 250 global news sources.

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Showing "Cell Signaling Technologies" News Articles 1–25 of 12,000+


Graphene Could Strengthen Nerve Signaling in the Brain

ArticleGraphene could hold the key to increasing the strength of nerve cell signaling and enabling nerve cell membranes to pull in more cholesterol.

Human Cell Line for Studies on Signaling and Endocrine Cancer

The National Institute of Child and Human Development seeks interested parties to further co-developa cell line with mutations in PRKAR1A, associated with tumor formation, for use a diagnostic or research tool. Read more about Human Cell Line for Studies on Signaling and Endocrine Cancer

Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation

Non-cell-autonomous function of DR6 in Schwann cell proliferation

Death receptor 6 (DR6) is an orphan member of the TNF receptor superfamily and controls cell death and differentiation in a cell-autonomous manner in different cell types. Here, we report an additional non-cell-autonomous function for DR6 in the peripheral nervous system (PNS). DR6-knockout (DR6 KO) mice showed precocious myelination in the PNS. Using an in vitro myelination assay, we demonst...

Corvus Pharmaceuticals Announces Presentation of New Data from Preclinical Study of Novel T-Cell Signaling Pathway Inhibitor at 10th Annual T-Cell Lymphoma Forum

BURLINGAME, Calif., Feb. 01, 2018 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc. (NASDAQ:CRVS), a clinical-stage biopharmaceutical company focused on the development and commercialization of precisely targeted oncology therapies, today announced new data from an ongoing preclinical study of its investigational small molecule T-cell signaling pathway inhibitor. Results showed that this orall...

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

The Fos-related antigen 1 (FRA-1) transcription factor promotes tumor cell growth, invasion and metastasis. Phosphorylation of FRA-1 increases protein stability and function. We identify a novel signaling axis...

Cell signaling interaction may prevent key step in lung cancer progression, study shows

A novel cell signaling interaction that may prevent a key step in lung cancer progression, new findings reveals.

Cell-Based Cancer Therapy Prodded by Custom IL-2 Keeps Going and Going

Whether you spare the rod or wield it freely, you risk spoiling the cell-based cancer therapy. The rod in this case is interleukin-2 (IL-2), a signaling chemical that awakens T cells to their cancer-fighting duties. Letting up on the IL-2 allows T cells to err on the side of sloth. Persistent administration, however, raises the risks of serious side effects. To circumvent this dilemma, scienti...

T cell antigen receptors act alone: Longstanding immunological mystery solved

(Vienna University of Technology) With a standard electron microscope, only dead T cells can be studied. Therefore, it is very hard to figure out the inner workings of the cell. New microscopy techniques, making it possible to study living T cells, have now led to surprising results: while it has been generally believed that T cell receptors must interact with one another for effective immune-sign...

Expression of enhancer of zeste homolog 2 (EZH2) protein in histiocytic and dendritic cell neoplasms with evidence for p-ERK1/2-related, but not MYC- or p-STAT3-related cell signaling

Advanced Image of A2aAR Protein Could Lead to Better Drug Design Methods

A Scripps Research Institute (TSRI) team reports that it has found structural features in a key protein used in drug design that may lead to new ways to target diseases. The A2A adenosine receptor (A2aAR) belongs to the G-protein-coupled receptor (GPCR) family, which is the target of roughly 40 percent of all approved pharmaceuticals.  The new, more detailed image of A2aAR's signaling...

Immunology Research Set to Change after Study Shows T-Cell Antigen Receptors Act Alone

Researchers at TU Wien and the Vienna School of Medicine report that T-cell receptors act alone, rather than interact with one another, for effective immune signaling. Their study (“ Monomeric TCRs drive T cell antigen recognition ”) appears in  Nature Immunology . “T-cell antigen recognition requires T cell antigen receptors (TCRs) engaging MHC-embedded antigenic peptides (pMH...

Androgen Receptor Linked to Different Metastases in RCC

Researchers have discovered that androgen signaling can either stimulate or suppress tumor cell movement and invasion to different locations in the body in patients who have renal cell carcinoma.

Spaceflight activates cell changes with implications for stem cell-based heart repair

(Mary Ann Liebert, Inc./Genetic Engineering News) A new study of the effects of spaceflight on the development of heart cells identified changes in calcium signaling that could be used to develop stem cell-based therapies for cardiac repair.

Researchers use 'top-down proteomics' strategy to get new insights into cancer

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.

CiteAb Names Cell Signaling Technology Antibody Company of the Year

“Antibody Company of the Year” and “Antibody Company Succeeding in Cancer Biology" DANVERS, Mass. (PRWEB) February 15, 2018 Cell Signaling Technology. Inc. (CST), a leading provider of antibodies, kits, and services, is honored with the 2018 CiteAb Award for “Antibody Company of the Year” and “Antibody Company Succeeding in Cancer Biology.” CST was also highly commended for the...

Cell Signaling Research Catalog

This 500-page catalog features listings and descriptions on over 1000 bioreagents and research kits, used for research in cell biology and

Crucial role of miR-31 in induction of CD8+ T-cell exhaustion and reinforcement of type 1 interferon signaling

Wnt signaling induces radioresistance through upregulating HMGB1 in esophageal squamous cell carcinoma

The impact of adhesion molecules on the in vitro culture and differentiation of stem cells

The term "cell adhesion" represents cell‐cell interactions and the interaction between the cell and the extracellular matrix (ECM). These interactions are crucial for the development of the stem cells niche to determine stem cell shape. The ECM is considered as a natural niche for cell residence. Cell adhesion molecules (CAMs) enable cell‐cell interactions and the interactions between the cell...

SMAD4 feedback regulates the canonical TGF-β signaling pathway to control granulosa cell apoptosis

Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway

PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway

Endothelial-specific m6A modulates mouse hematopoietic stem and progenitor cell development via Notch signaling

Cell biology: Positioning the cleavage furrow

(Ludwig-Maximilians-Universität München) Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell.

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