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Cell Migration Assay Trends 2017 [Updated: 20022017] Prices from USD $2000

03:33 EST 27 Feb 2017 | BioPortfolio Report Blog

HTStec's Cell Migration Assays Trends 2017 report was published on 20 February 2017. This 49 page market report summarizes the results of HTStec's second global webbased benchmarking survey on cell migration assays carried out in February 2017. The study was initiated by HTStec as part of its tracking of emerging life science marketplaces and to update HTStec's previous report on the topic August 2012. The questionnaire was compiled by HTStec to address the needs and interests of the cell migration assay vendor community and those of our sponsor, who was a technology developer that plans to launch a new next generation' cell migration assay kit in the near future. The main objectives were to comprehensively document and understand the current use of cell migration assays, assay metrics, limitations and preferences. The survey also examined the requirements for a 'next generation' cell migration assay, important attributes, pricing and future adoption. Equal emphasis was given to soliciting opinion from all areas were cell migration assays are deployed. The report is based on 59 responses from Basic and Applied Research Labs mainly in North America and Europe.
Executive Summary
This market report summarizes the results of HTStec's second global webbased benchmarking survey on cell migration assays carried out in February 2017.
The study was initiated by HTStec as part of its tracking of emerging life science marketplaces and to update HTStec's previous report on the topic August 2012.
The questionnaire was compiled by HTStec to address the needs and interests of the cell migration assay vendor community and those of our sponsor, who is a technology developer that plans to launch a new next generation' cell migration assay kit in the near future.
The main objectives were to comprehensively document and understand the current use of cell migration assays, assay metrics, limitations and preferences. The survey also examined the requirements for a 'next generation' cell migration assay, important attributes, pricing and future adoption.
Equal emphasis was given to soliciting opinion from all areas were cell migration assays are deployed.
The survey looked at the following aspects of cell migration assays, as practiced today 2017 and in some cases as predicted for the future 2019: key enduser grouping respondents belong to; disease or research areas currently investigating/targeting; most important applications; use of different assay types; detection instrument types used to read or analyze assays cell migration assays; use of different cell types; how many cell migration assays are run per year and per separate experiment; number of times cell migration assays are repeated to confirm a real trend; types of culture vessels used to perform cell migration assays; % of cell migration assays that are home brew vs. a commercial assay kit or product; main limitations of existing assay products; how well do cell migration assay results help in prioritizing compounds or cell therapies for further development; main limitations of existing assays; preference for alternative cell migration offerings; suggestions for improving existing cell migration assays; value placed on extra features which might be added to a next generation' assay; interest in finding an alternative improved next generation' assay; likelihood of adopting a next generation' assay; maximum price premium respondents would consider paying for a next generation' cell migration assay; attributes respondents most want to access in future cell migrationrelated research efforts; type of information a technology developer of a next generation' cell migration assay must provide to promote adoption; average cost per single assay well undertaken and cost willing to pay for a next generation' assay well; annual budgets for cell migration assay consumables; % of consumables budget allocated to commercial assay kits; most purchased from suppliers of cell migration assays kits; any unmet needs or areas for improvement; and respondents who want more information about a next generation' cell migration assay product.
The main questionnaire consisted of 28 multichoice questions and 2 openended questions. In addition, there were 6 questions related solely to survey demographics.
The survey collected 59 validated responses, of these 82% provided comprehensive input.
Survey responses were geographically split: 42% North America; 34% Europe; 14% Asia excluding Japan; 3% Japan; 3% Rest of World; 2% South America; and 2% China.
Survey respondents were drawn from persons or groups undertaking cell migration assays and using or planning to use cell migration assay kits or related products.
Respondents came from 46 University/Research Institute/Government Lab/NotforProfit Facilities; 5 Medical Schools/Hospitals/Clinics; 4 Academic Screening Centers; 2 Large Pharma; 1 MediumSmall Pharma; and 1 Small RD Company.
Most survey respondents had a senior job role or position which was in descending order: 15 professors/ assistant professors; 10 principal investigators; 8 research scientists/associates; 5 postdocs; 5 section/ group leaders; 5 senior scientists/researchers; 4 lab managers; 2 department heads; 2 directors; 2 others; and 1 vice president.
Survey results were expressed as an average of all survey respondents. In addition, where appropriate the data was reanalyzed after subdivision into the following 5 survey groups: 1 Basic/Academic Research; 2 Applied Research; 3 Oncology Focus; 4 Europe; and 5 North America.
The key cell migration grouping of the majority of respondents was basic/academic research.
The disease area most investigated/targeted with cell migration was oncology/cancer.
Metastasis and tumor invasion was rated the most important application/reason for investigating cell migration assays.
The assay type most used today for cell migration was the Boyden chamber, sometimes referred to as the transmembrane or chemotaxis assay.
The type of instrument most used to read or analyse cell migration assays was a conventional brightfield or phase microscope.
The cell type most used today for cell migration assays was tumor cell lines.
A median of 50100 cell migration assays wells were run per lab per year today.
A median of 1150 cell migration assays wells were run per separate experiment today.
A median of 3 replicate assays were run to be convinced that the migration data trend identified was real.
The type of cell culture vessels most used today for cell migration assays were 6well plates.
Almost 50% of cell migration assays today were made with a commercial assay kit or consumable product.
The median predictive ranking power of cell migration assays today was medium i.e. 2575% of the time it will help to prioritize compounds for further development.
Quantification of migratory cells based on endpoint measurement alone was rated the major hurdle/greatest limitation of existing cell migration assays.
The level of agreement with various alternative cell migration offerings was most positive for Prefer robust, reproducible assays, even if they are slightly more expensive VERSUS simple end point assays'.
Some suggestions on how to improve existing cell migration assays were documented.
Greater reproducibility between different end users, was rated the feature most wanted added to a next generation' cell migration assay.
The opinion of the most respondents on finding an alternative next generation' cell migration assay was medium priority i.e. we would consider evaluating any new assays on its merits.
The median probability of adopting a next generation' cell migration assay over the coming years was likely 5175% likelihood.
Respondents reported they would pay a median price premium of 0.5x increase above the price of a Transwell assay for a next generation' cell migration assay.
The attribute most want to access in their future cell migrationrelated research efforts was the ability to perform single cell assessments of heterogeneous cell populations.
Free trial assay kits were rated as the information/materials a technology developer of a next generation' cell migration assay must provide to promote adoption.
The average cost per single cell migration assay irrespective of well size was a median of $0.75$1.00.
The median reasonable price for a single next generation' cell migration assay was $1.00$2.00.
The median annual budget for cell migration assays consumables allocated today was $2.5K$5K.
Around 50% of the cell migration assays consumables budget was allocated to commercial assay kits.
A bottom up model was developed to estimate the global market for cell migration assay consumables using data collected in the survey % of cell migration assays that use a commercial assay kit or product and the mean annual budget allocated for cell migration assay consumables. This model gave an estimate in excess of $20M in 2017. Segmentation and CAGR estimates are given in the full report.
The main suppliers of cell migration assay kits purchased were Corning, ThermoFisher Scientific, Ibidi and MilliporeSigma.
45 respondents would like to receive more information about a 'next generation' cell migration assay.
33 respondents were interested in performing inlab evaluations/providing feedback on a 'next generation' cell migration assay.
14 respondents were willing to be contacted to discuss their cell migration assay requirements further.
Some limited feedback on unmet needs or areas for improvement with respect to cell migration assays were documented.
The full report provides the data, details of the breakdown of the responses for each question, its segmentation and the estimates for the future 2019. It also highlights some differences between the survey groups, particularly between the Applied Research or Europe and the other groupings.
In this survey and report we use the term cell migration assays' to encompass all assay types involving cell movement including: cell migration, transmigration, cell motility, wound healing, chemotaxis, haptotaxis, cell invasion and cell exclusion.

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