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Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer

17:25 EDT 19 Jun 2017 | Nature Publishing

Vijayanand and colleagues use genome-wide RNA sequencing for transcriptional profiling of CD8+ T cells from tumors and adjacent uninvolved lung tissue from patients with early-stage lung cancer. A tissue-resident memory signature is associated with enhanced cytotoxicity and improved survival.

Original Article: Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer

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