£3 million awarded to pain research

20:00 EDT 18 Jun 2017 | Arthritis Research UK

The pain challenge seeks to fund research that will increase our understanding of the fundamental biological mechanisms and pathways which underlie musculoskeletal pain and which may lead to the prevention, identification or development of new treatments for pain.

The first call for applications for our pain challenge was launched in early 2016, and we invested a total of over £3 million in 13 projects as part of this round. We wanted to tell you about all the exciting projects that we funded as part of this first call:

Dr Chantal Chenu (The Royal Veterinary College)
The role of the nerve growth mediator semaphorin-3A in joint pain

Dr Michael Lee (University of Cambridge) Exploring whether repeated exposure to pain in fibromyalgia alters the brain signalling process

Professor Stuart Bevan (King’s College London)Role of the nerve protein TRPM3 in the development and maintenance of pain in osteoarthritis

Dr Ben Seymour (University of Cambridge)
UK Japan Pain, Action and Movement Network

Dr David Andersson (King’s College London)
Understanding what causes pain in complex regional pain syndrome
Dr Jenny Lewis (University of the West of England)

Using illusions to explore brain processes in people with musculoskeletal pain
Professor Susan Brain (King’s College London)

Role of the nerve protein TRPC5 in the development of pain and inflammation in osteoarthritis

Dr Fiona Watt (University of Oxford)
Can we predict risk of knee pain and painful osteoarthritis following knee joint injury?

Dr Ikhlas El karim (Queen’s University Belfast)

Improving understanding of the pain experienced in temporomandibular disorders

Professor Francesco Dell'Accio (Queen Mary University of London)

The role of agrin in the cause and treatment of osteoarthritis

Dr Simon Jones (University of Birmingham)

Identifying the role of lncRNAs in inflammatory pain of osteoarthritis

Dr Christopher Brown (University of Liverpool)

Using mathematical models to identify brain changes in people with chronic pain

Professor Peter McNaughton (King’s College London)

Investigating how the nerve proteins HCN2 and AT2 contribute to pain in arthritis

Building on this activity, in May 2016 and February 2017 we held two large and successful workshops which brought together people with arthritis, healthcare professionals, researchers, other funders and organisations to identify unmet patient and research needs, gaps in our knowledge, barriers and challenges for pain research.

Our 2017/18 pain challenge call, which is now inviting applications, uses the insight gained from our workshops to launch a broad and ambitious pain challenge, which will span all areas of our research activity. Through this new challenge call we hope to build on the recent advances made in pain research to make a significant leap forward in our understanding of musculoskeletal pain, how it is managed and how it may be prevented. The outline application deadline is Thursday 31 August 2017.

Original Article: £3 million awarded to pain research


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