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To the Editor In his Viewpoint, Dr Ioannidis highlighted the seriousness of the nonreproducibility of preclinical research and suggested various ways to improve the situation. Two points are of concern. First, he wrote that “Overall, basic and preclinical research probably have a much larger challenge of nonreproducibility than clinical research.” The reverse is more likely to be true. Clinical research may be infeasible to reproduce for at least 2 reasons: the cost of doing so may be prohibitive and both background and foreground conditions may be impossible to replicate adequately.
Original Article: Nonreproducibility of Preclinical ResearchNEXT ARTICLE
Clinical Research Organization
Contract Research Organization (CRO) provide research services outsourced on a contract basis to the pharmaceutical, biotechnology, healthcare and medical device industries: biopharmaceutical development biologic assay development commercial...