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Skin Microbiome Can Be Negatively Altered by Topical Antibiotics

07:05 EDT 21 Jun 2017 | Genetic Engineering News

Scientists at the Perelman School of Medicine at the University of Pennsylvania say the use of topical antibiotics can dramatically alter communities of bacteria that live on the skin, while the use of antiseptics has a much smaller, less durable impact. The study ("Topical antimicrobial treatments can elicit shifts to resident skin bacterial communities and reduce colonization by  Staphylococcus aureus  competitors"), published in  Antimicrobial Agents and Chemotherapy,  was conducted in mice in the laboratory of Elizabeth Grice, Ph.D., an assistant professor of dermatology, and reportedly is the first to show the long-term effects of antimicrobial drugs on the skin microbiome.  In the gut, research shows medication that alters microbial communities can lead to complications like  Clostridium difficile , which causes diarrhea and is the most common hospital-acquired infection. But when it comes to the skin, the impact of these medications on bacteria strains like  S. aureus , the most common cause ...

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