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Anti-Alzheimer’s Compounds Found in Medicinal Plant Via New Drug Discovery Strategy

08:08 EDT 21 Jun 2017 | Genetic Engineering News

Traditional medicinal plants have been valued over the years for providing insight into an array of diseases. However isolating specific efficacious molecules from the milieu of compounds that constitute most plant species can be a daunting task. Now, researchers at the University of Toyama, Japan have developed a method to isolate and identify active compounds in plant medicines. New data—published recently in Frontiers in Pharmacology in an article entitled, “ A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer’s Disease and Its Target Molecule ", demonstrate that a new technique identifies several active compounds from Drynaria  rhizome, a traditional plant medicine, that improve memory and reduce disease characteristics in a mouse model of Alzheimer's disease. Typically, scientists will repeatedly screen crude plant medicines in lab experiments to see if any compounds show an effect on cells grown in vitro . If a compound shows a positive effect in ...

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