CRUK Calls for New Research Proposals in Second Phase of Grand Challenge

04:26 EDT 22 Jun 2017 | Genetic Engineering News

Cancer Research UK (CRUK) has launched the second phase of its Grand Challenge program, which awards funding to interdisciplinary research teams from around the world to help address some of the key issues in fundamental cancer research, diagnosis, drug discovery and development. In February CRUK announced the four teams, and their projects, which were selected to share in the first, £71 million tranche of funding . The charity has now thrown down the gauntlet to researchers worldwide to get together and devise projects addressing any one of another eight key challenges. • Devise approaches to prevent or treat cancer based on mechanisms that determine tissue specificity of some cancer genes • Create novel tumour vaccinology approaches that establish or enhance successful immune responses beyond what is revealed by current checkpoint therapy • Define mechanistic rules for combinatorial treatments to overcome resistance and avoid toxicity • Distinguish between lethal ...

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