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Researchers show how a protein prevents the uncontrolled expansion of immune cells

04:26 EDT 22 Jun 2017 | Medical Xpress

The mammalian immune system consists of millions of individual cells that are produced daily from precursor cells in the bone marrow. During their development, immune cells undergo a rapid expansion, which is interrupted by phases of differentiation to more mature lymphocytes. Alternate phases of proliferation and differentiation occur also during the maturation of antibody-producing B cells. Researchers in Prof. Dr. Michael Reth's laboratory have come one step closer to understand how the proliferation to differentiation switch in B lymphocytes works, thereby providing new insights into the development of the most common types of tumors in children and potential therapies thereof.

Original Article: Researchers show how a protein prevents the uncontrolled expansion of immune cells

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