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Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach

11:09 EDT 29 Jun 2017 | Nature Publishing

Leushacke et al. provide insights into the role of Lgr5 cells in the oxyntic stomach, demonstrating that they label a subpopulation of chief cells that function as reserve stem cells during regeneration and cells-of-origin of gastric cancer.

Original Article: Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach

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