Advertisement

Topics

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

11:09 EDT 29 Jun 2017 | Nature Publishing

Wang et al. show that lipid-induced ROS lead to ACAT2 stabilization by oxidizing a cysteine residue, thereby preventing its ubiquitylation and ACAT2 degradation. They further show that ACAT2 stabilization improves lipotoxicity and insulin resistance.

Original Article: Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

NEXT ARTICLE

More From BioPortfolio on "Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Endocrine Disorders
Endocrine disorders are grouped into two categories: hormone imbalance - when a gland produces too much or too little of an endocrine hormone development of lesions (such as nodules or tumors) in the endocrine system, which may or may not affect...