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AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

11:09 EDT 29 Jun 2017 | Nature Publishing

Zhou et al. show that in the context of AML1-ETO-driven leukaemia, AES and DDX21 induce small nucleolar RNA (snoRNA)–ribonucleoprotein (RNP) formation and this is important for self-renewal of leukaemic cells.

Original Article: AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

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