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Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin

11:09 EDT 29 Jun 2017 | Nature Publishing

Ban et al. show that optic atrophy 1 (OPA1) and cardiolipin mediate mitochondrial fusion. In contrast, a homotypic trans-OPA1 interaction independent of cardiolipin mediates membrane tethering to form mitochondrial cristae.

Original Article: Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin

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