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Elevated adipsin linked with pulmonary arterial hypertension in patients with systemic sclerosis

13:00 EDT 30 Jun 2017 | Healio

Among patients with systemic sclerosis, elevated levels of adipsin were linked with pulmonary arterial hypertension, according to a recently published analysis.“Taken together, these findings suggest a previously unrecognized pathogenic role for adipsin in [systemic sclerosis] SSc and SSc [pulmonary arterial hypertension] PAH, and highlight adipsin as a novel marker of vascular manifestations with important prognostic and potentially therapeutic value,” Benjamin D. Korman, MD, from Northwestern University, and colleagues wrote. “Moreover, in light of the essential role of adipsin in modulating complement pathway activity, our results implicate the complement system in SSc-associated PAH.”

Original Article: Elevated adipsin linked with pulmonary arterial hypertension in patients with systemic sclerosis

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