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Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis

20:00 EDT 29 Jun 2017 | Breast Cancer Research

The importance of the mTOR complex 2 (mTORC2) signaling complex in tumor progression is becoming increasingly recognized. HER2-amplified breast cancers use Rictor/mTORC2 signaling to drive tumor formation, tumor ...

Original Article: Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis

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