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Mitochondrial control of immunity: beyond ATP

19:21 EDT 3 Jul 2017 | Nature Publishing

Does mitochondrial metabolism simply support the bioenergetic and biosynthetic needs of committed immune cells, or does it also control their fate? In this Review, Chandel and colleagues explore variations in mitochondrial metabolism across different immune cells and discuss how mitochondria can act as important signalling organelles to dictate immune cell function.

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