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Treatment of membranous nephropathy: time for a paradigm shift

19:48 EDT 3 Jul 2017 | Nature Publishing

Membranous nephropathy is an immune-mediated disease and is the leading cause of nephrotic syndrome in adults. Here, the authors discuss the role of B cell-depleting regimens in the treatment of this disease and the potential use of rescue therapy with agents that target plasma cells, which might prevent antigen–antibody interactions and immune complex-mediated complement activation.

Original Article: Treatment of membranous nephropathy: time for a paradigm shift

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