Advertisement

Topics

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

20:09 EDT 3 Jul 2017 | Nature Publishing

Several natural and unnatural lissoclimide cytotoxins have been prepared via semi-synthesis and total synthesis. An X-ray co-crystal structure of chlorolissoclimide with the ribosome and evaluation of cytotoxicity and translation inhibition of new compounds in the series improves our understanding of the molecular basis for cytotoxicity.

Original Article: Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides

NEXT ARTICLE

More From BioPortfolio on "Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Radiology
Radiology is the branch of medicine that studies imaging of the body; X-ray (basic, angiography, barium swallows), ultrasound, MRI, CT and PET. These imaging techniques can be used to diagnose, but also to treat a range of conditions, by allowing visuali...