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Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin

20:14 EDT 3 Jul 2017 | Nature Publishing

The size of immune-cell populations needs to be tightly regulated. Shinohara and colleagues demonstrate that intracellular and secreted osteopontin control the contraction and expansion of myeloid and lymphoid populations differently under infectious and autoimmune conditions.

Original Article: Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin

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