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Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

21:13 EDT 3 Jul 2017 | Nature Publishing

Microglia are the macrophages of the CNS, with innate neuroimmune function, and play important roles in tissue homeostasis, CNS development and neurodegeneration. Here human microglial gene expression profiles were generated. Human and mouse microglia were highly similar, except for aging-regulated genes, indicating that microglial aging differs between humans and mice.

Original Article: Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

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