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Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary

20:59 EDT 4 Jul 2017 | Nature Publishing

The identification of the tissue of origin in patients with cancer of unknown primary (CUP) is an example of how epigenomics can be incorporated in clinical settings. Epigenetic and other molecularly-based diagnostic strategies have emerged to complement traditional diagnostic procedures, thereby improving the clinical management of patients with CUP. Herein, the authors present the latest data on strategies using epigenetics and other molecular biomarkers to guide therapeutic decisions involving patients with CUP, addressing a previously unmet need.

Original Article: Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary

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