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CNIC scientists discover an essential mechanism in the immune response

20:00 EDT 4 Jul 2017 | AAAS

(Centro Nacional de Investigaciones Cardiovasculares) Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have discovered that the transcriptional regulator CTCF plays an essential role in antibody production. The study, led by Dr. Almudena Ramiro and published in Nature Communications, demonstrates that CTCF is essential for the ability of B lymphocytes to correctly protect the body against infection by pathogens. The research team shows that in the absence of CTCF, the immune system does not function correctly, a finding with implications for vaccine research.

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