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This Review considers how forkhead box protein P3 (FOXP3) — the key transcription factor of regulatory T (Treg) cells — is regulated both at the transcriptional level and through post-translational modifications. The authors explain how FOXP3 interacts with other molecules to induce and maintain Treg cell populations, and they discuss the potential of therapeutically targeting FOXP3 in the context of human disease.
Original Article: The regulation of immune tolerance by FOXP3NEXT ARTICLE
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...