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The ability of clinicians to discriminate between bacterial and viral infections among their patients is critical, not only to administer the appropriate therapeutic intervention but to help quell the rise in a major global health threat—antibiotic resistance stemming from overuse. Unfortunately, ailments such as lower respiratory tract infections (LRTI) symptomatically present with similar clinical symptoms, regardless of the root pathogen—making proper diagnosis difficult. Now, investigators at the University of Rochester Medical Center (URMC) have recently released finding from a new study that utilized the power of RNA sequencing (RNA-Seq) and transcriptomic analysis to help physicians prescribe antibiotics to patients who need them, and avoid giving them to individuals who don't. Results from the new study were published recently in Scientific Reports through an article entitled “ Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness .” “It's extremely difficult to interpret what's ...
Original Article: RNA-Seq Used to Discriminate between Bacterial and Viral InfectionsNEXT ARTICLE
MRSA (methicillin-resistant Staphylococcus aureus)
MRSA (methicillin-resistant Staphylococcus aureus) is a family of bacteria with resistance to one or more major antibiotics. There are currently 17 different strains of MRSA. Two particular strains, EMRSA15 and EMRSA16 account for 96% of MRSA blood...
Asthma COPD Cystic Fibrosis Pneumonia Pulmonary Medicine Respiratory Respiratory tract infections (RTIs) are any infection of the sinuses, throat, airways or lungs. They're usually caused by viruses, but they can also ...
DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule. During DNA sequencing, the bases of a small fragment of DNA are sequentially identified from signals emitted as each fragment is re-synthesized from a ...