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They have a taste for our blood, particularly the iron it contains, and they can leave us sickened, weakened, even dead. They are Staphylococcus aureus bacteria, and their depredations are linked with up to 50,000 deaths each year in the United States. Should these microbial vampires resist antibiotics, as they often do when they manifest as hospital-acquired infections, they won’t be deterred by garlic, wolfsbane, or sacred objects. They may, however, be vulnerable to light—provided they are also exposed to an enzyme-activating small molecule. The small molecule, called ’882 for short, has been identified as a potential S. aureus killer by scientists based at the Vanderbilt University School of Medicine. So far, these scientists, led by Eric Skaar, Ph.D., have evaluated ’882 in mouse models of skin and soft tissue infections. The results have been encouraging. In combination with light, the small molecule can reduce bacterial ...
Original Article: Microbial Vampires Shrink from LightNEXT ARTICLE
Enzymes are proteins that catalyze (i.e., increase the rates of) chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical re...
Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...