Adipose-derived stem cell transplantation shows promise for keratoconus

14:00 EDT 2 Aug 2017 | Healio

A phase 1 study showed the safety of autologous adipose-derived adult stem cell transplantation in the corneal stroma, including the ability of the cells to survive in vivo and produce a small amount of new collagen. This form of cellular therapy could potentially help remodel and strengthen the cornea in patients with keratoconus.The prospective study was set up as a cooperation among the research, development and innovation department of Vissum Instituto Oftalmologico de Alicante, Spain, and several international partners. It enrolled five consecutive patients with advanced keratoconus who underwent liposuction and transplantation of autologous adipose-derived adult stem cells in a femtosecond laser-created stromal pocket. Four patients completed the 6 months of follow-up.

Original Article: Adipose-derived stem cell transplantation shows promise for keratoconus


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