Protein critical to early stages of cellular HIV infection identified

20:00 EDT 7 Aug 2017 | AAAS

(Tokyo Medical and Dental University) A Tokyo Medical and Dental University (TMDU) -led research team identified a protein, MELK, required for the HIV-1 virus to efficiently infect its target cells. MELK, produced by the cell, is necessary for removal of the protein coat around the HIV-1 virus, which is essential for the infection process. The team further revealed that MELK modifies the protein coat at a specific location to promote its removal. These findings offer a potential new target for anti-HIV treatment.

Original Article: Protein critical to early stages of cellular HIV infection identified


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