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In determining treatment for patients with glucocorticoid-induced osteoporosis, clinicians and patients should collaborate on decision-making based on patient values, preferences and comorbidities, according to recent guidelines published by the American College of Rheumatology.In the systematic review, researchers queried English-language literature databases, including OVID Medline, PubMed, Embase and the Cochrane Library for published literature about the benefits and harms of glucocorticoid-induced osteoporosis prevention and treatment. Data were collected from the inception of the databases until Oct. 6, 2015. The researchers used the grading of recommendations assessment, development and evaluation methodology to rate the quality of evidence. They developed and applied clinical questions (population/intervention/comparator/outcomes [PICO]). These PICO questions pertained to assessment and reassessment of fracture risks, treatment comparisons, and treatment duration and reassessment. The direction and strength of each recommendation in relation to each PICO question was determined by a voting panel that consisted of adult and pediatric rheumatologists, internists, a nephrologist, a pulmonologist, a gastroenterologist, experts in treating glucocorticoid-induced osteoporosis and a patient.NEXT ARTICLE
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...
Collaborations in biotechnology
Commercial and academic collaborations are used throughout the biotechnology and pharmaceutical sector to enhance research and product development. Collaborations can take the form of research and evaluation agreements, licensing, partnerships etc. ...